HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: SNX6 (Q9UNH7)
Sorting nexin-6 (TRAF4-associated factor 2) [Cleaved into: Sorting nexin-6, N-terminally processed]
Gene: SNX6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30442766
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043524 - negative regulation of neuron apoptotic process
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 406
+	Hs
		375016 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		SNX6_HUMAN (1-406): 6.86e-126: 371: 100.00
+	Hs
		374282 RASN_HUMAN (1-189): 3.16e-85: 251: 85.19		SNX6_HUMAN (1-406): 6.86e-126: 371: 100.00
+	Hs
		1145173 RAB35_HUMAN (4-187): 1.26e-82: 244: 31.28		SNX6_HUMAN (1-406): 6.86e-126: 371: 100.00
+	Hs
		976664 RB11A_HUMAN (4-184): 5.8e-73: 220: 33.88		SNX6_HUMAN (1-406): 6.86e-126: 371: 100.00
+	Hs
		375045 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		SNX5_HUMAN (13-405): 3.77e-112: 336: 64.38
+	Hs
		374306 RASN_HUMAN (1-189): 3.16e-85: 251: 85.19		SNX5_HUMAN (13-405): 3.77e-112: 336: 64.38
+	Hs
		376150 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		SNX5_HUMAN (13-405): 3.77e-112: 336: 64.38
+	Hs
		976698 RB11A_HUMAN (4-184): 5.8e-73: 220: 33.88		SNX5_HUMAN (13-405): 3.77e-112: 336: 64.38
+	Hs
		255427 RAB35_HUMAN (4-187): 1.26e-82: 244: 31.28		SNX2_HUMAN (16-404): 1.6e-93: 292: 21.31
+	Hs
		255410 RB11A_HUMAN (4-184): 5.8e-73: 220: 33.88		SNX2_HUMAN (16-404): 1.6e-93: 292: 21.31
+	Hs
		976254 RB11A_HUMAN (4-184): 5.8e-73: 220: 33.88		SNX1_HUMAN (32-404): 3.58e-86: 273: 20.96
+	Hs
		376149 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		SNX9_HUMAN (25-402): 1.44e-80: 260: 12.41
+	Hs
		957945 RAB14_HUMAN (4-184): 2.96e-72: 219: 29.51		SNX30_HUMAN (21-403): 2.21e-75: 242: 15.42
+	Hs
		329831 RB11A_HUMAN (4-184): 5.8e-73: 220: 33.88		SNX4_HUMAN (14-403): 5.03e-57: 195: 15.54
+	Hs
		958058 RAB14_HUMAN (4-184): 2.96e-72: 219: 29.51		SNX8_HUMAN (39-403): 5.44e-54: 187: 16.54
+	Hs
		249548 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		SNX3_HUMAN (32-170): 3.09e-14: 71.7: 20.28
+	Hs
		249549 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		SNX3_HUMAN (32-170): 3.09e-14: 71.7: 20.28
+	Hs
		249598 RAB2A_HUMAN (4-183): 1.47e-74: 224: 32.97		SNX3_HUMAN (32-170): 3.09e-14: 71.7: 20.28
+	Hs
		249602 RB11A_HUMAN (4-184): 5.8e-73: 220: 33.88		SNX3_HUMAN (32-170): 3.09e-14: 71.7: 20.28