HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 1191
+	Hs
		375013 RAF1_HUMAN (1-648): 0: 652: 100.00		CHD7_HUMAN (491-1004): 4.82e-13: 76.2: 7.21
+	Hs
		257542 RAF1_HUMAN (1-648): 0: 652: 100.00		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Hs
		325588 RAF1_HUMAN (1-648): 0: 652: 100.00		LATS1_HUMAN (518-1066): 1.1e-09: 65: 11.05
+	Hs
		373932 RAF1_HUMAN (1-648): 0: 652: 100.00		SC24C_HUMAN (362-642): 1.58e-09: 64.6: 12.98
+	Hs
		542878 BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88		MDC1_HUMAN (442-806): 1.14e-11: 71.8: 12.21
+	Hs
		522749 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		MUC1_HUMAN (344-901): 6.29e-21: 102: 9.70
+	Hs
		64077 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		L37A2_HUMAN (497-1142): 1.97e-10: 67.7: 8.67
+	Hs
		325610 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		LATS1_HUMAN (518-1066): 1.1e-09: 65: 11.05
+	Hs
		523092 SRC_HUMAN (331-607): 3.01e-106: 333: 33.45		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77
+	Hs
		412362 FYN_HUMAN (337-607): 2.33e-103: 326: 34.55		MAGE1_HUMAN (459-823): 2.66e-11: 70.3: 14.21