Protein: DOCK9
Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1) (Zizimin-1)

Gene: DOCK9
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q9BZ29

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0007264 - small GTPase-mediated signal transduction
GO:0012505 - endomembrane system
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1206375

DOC11
Dedicator of cytokinesis protein 11

3

12

High-throughput

0.817

High

1385154

DOC10
Dedicator of cytokinesis protein 10

2

13

High-throughput

0.811

High

955556

CDC42
Cell division control protein 42 homolog

2

20

Small-scale

0.768

High

375912

RASK
GTPase KRas

2

20

High-throughput

0.754

High

978272

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

1122816

DOCK1
Dedicator of cytokinesis protein 1

2

13

High-throughput

0.737

High

889497

CLK1
Dual specificity protein kinase CLK1

1

3

High-throughput

0.625

High

126781

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

374903

RASH
GTPase HRas

1

20

High-throughput

0.618

High

581269

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

601431

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

920259

PLK1
Serine/threonine-protein kinase PLK1

1

9

High-throughput

0.618

High

953651

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

988679

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1015748

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

1145093

RAB35
Ras-related protein Rab-35

1

6

High-throughput

0.618

High

1419481

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

730213

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.601

High

966838

1433G
14-3-3 protein gamma

2

20

High-throughput

0.601

High

990694

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.601

High

1049743

1433F
14-3-3 protein eta

2

20

High-throughput

0.601

High

167645

GIPC1
PDZ domain-containing protein GIPC1

2

0

High-throughput

0.585

High

1419480

PAAT
ATPase PAAT

2

1

High-throughput

0.574

High

1014606

SMAD3
Mothers against decapentaplegic homolog 3

1

4

Small-scale

0.554

High

1153900

SMAD2
Mothers against decapentaplegic homolog 2

1

4

Small-scale

0.554

High

1419478

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.553

High

1419479

PKHA4
Pleckstrin homology domain-containing family A member 4

1

15

High-throughput

0.553

High

977073

CNBP
CCHC-type zinc finger nucleic acid binding protein

2

0

High-throughput

0.547

High

635551

NEBU
Nebulin

1

3

High-throughput

0.541

High

1116447

FHL1
Four and a half LIM domains protein 1

1

4

High-throughput

0.541

High

1127369

CASL
Enhancer of filamentation 1

1

4

High-throughput

0.541

High

1115403

CUL4B
Cullin-4B

1

6

High-throughput

0.536

High

160128

CHD1
Chromodomain-helicase-DNA-binding protein 1

2

1

High-throughput

0.521

High

317673

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.518

High

333397

SNAPN
SNARE-associated protein Snapin

1

0

High-throughput

0.518

High

1158079

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

1

0

High-throughput

0.518

High

1419482

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

0

High-throughput

0.517

High

535501

BIP
Endoplasmic reticulum chaperone BiP

1

6

High-throughput

0.515

High

639817

TAF1
Transcription initiation factor TFIID subunit 1

1

2

High-throughput

0.494

High

1419483

MYOTI
Myotilin

1

4

High-throughput

0.494

High

251650

CCNT1
Cyclin-T1

1

2

High-throughput

0.479

High

476190

ANXA5
Annexin A5

1

4

High-throughput

0.479

High

556324

CADH1
Cadherin-1

1

2

High-throughput

0.479

High

971965

1433E
14-3-3 protein epsilon

1

9

High-throughput

0.479

High

987197

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

3

High-throughput

0.479

High

1131819

LBR
Delta(14)-sterol reductase LBR

1

1

High-throughput

0.479

High

1338352

FBX22
F-box only protein 22

1

2

High-throughput

0.479

High

959048

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.458

High

843953

HD
Huntingtin

1

3

High-throughput

0.457

High

1348487

LNX1
E3 ubiquitin-protein ligase LNX

1

6

Small-scale

0.439

High

845786

MUC18
Cell surface glycoprotein MUC18

1

3

High-throughput

0.437

High

1119994

CIRBP
Cold-inducible RNA-binding protein

1

4

High-throughput

0.437

High

1255408

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.437

High

1287073

MOB3B
MOB kinase activator 3B

1

11

High-throughput

0.437

High

1381951

CK052
Uncharacterized protein C11orf52

1

3

High-throughput

0.437

High

1419476

NSRP1
Nuclear speckle splicing regulatory protein 1

1

1

High-throughput

0.437

High

1419477

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

0

High-throughput

0.282

High

325098

HEXI1
Protein HEXIM1

1

0

High-throughput

0.249

Low

914741

RM12
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.249

Low

1204715

TAF7L
Transcription initiation factor TFIID subunit 7-like

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025