Protein: GNDS
Ral guanine nucleotide dissociation stimulator (RalGDS) (Ral guanine nucleotide exchange factor) (RalGEF)

Gene: GNDS, RALGDS
Organism: Homo sapiens
Interactions: 36
UniProt ID: Q12967

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005903 - brush border

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

374558

RASH
GTPase HRas

12

20

Small-scale

0.978

High

982070

RAP1A
Ras-related protein Rap-1A

4

20

Small-scale

0.879

High

518596

RAP2A
Ras-related protein Rap-2a

3

20

Small-scale

0.861

High

375467

RASK
GTPase KRas

3

20

Small-scale

0.852

High

959321

RAP1B
Ras-related protein Rap-1b

3

20

Small-scale

0.843

High

165124

RASM
Ras-related protein M-Ras

2

20

Small-scale

0.767

High

959437

RAP2B
Ras-related protein Rap-2b

2

20

Small-scale

0.767

High

967201

RRAS2
Ras-related protein R-Ras2

2

20

Small-scale

0.754

High

520685

RRAS
Ras-related protein R-Ras

1

20

Small-scale

0.680

High

1091743

RPGF2
Rap guanine nucleotide exchange factor 2

1

3

Small-scale

0.680

High

1091739

RIT1
GTP-binding protein Rit1

1

20

Small-scale

0.656

High

950466

KR108
Keratin-associated protein 10-8

2

2

High-throughput

0.606

High

1091741

RIT2
GTP-binding protein Rit2

1

20

Small-scale

0.590

High

1091734

RIN1
Ras and Rab interactor 1

1

0

Small-scale

0.589

High

885233

HXA1
Homeobox protein Hox-A1

2

0

High-throughput

0.580

High

955108

CDC42
Cell division control protein 42 homolog

1

11

Small-scale

0.575

High

70189

CRTP1
Cysteine-rich tail protein 1

2

1

High-throughput

0.553

High

732563

ARRB2
Beta-arrestin-2

1

1

Small-scale

0.552

High

760751

CD68
Macrosialin

1

0

High-throughput

0.518

High

578468

BRAF
Serine/threonine-protein kinase B-raf

1

7

High-throughput

0.506

High

400745

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

10

Small-scale

0.500

High

720467

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

1

Small-scale

0.481

High

481264

HMGB1
High mobility group protein B1

1

1

High-throughput

0.479

High

791347

SYUA
Alpha-synuclein

1

1

Small-scale

0.479

High

882468

ARRB1
Beta-arrestin-1

1

1

Small-scale

0.479

High

1091733

FADD
FAS-associated death domain protein

1

5

Small-scale

0.479

High

1091735

CASP8
Caspase-8

1

1

Small-scale

0.479

High

1091736

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.479

High

1091740

CNKR1
Connector enhancer of kinase suppressor of ras 1

1

2

Small-scale

0.479

High

1091738

C2D2B
Protein CC2D2B

1

1

High-throughput

0.470

High

1091742

P63
Tumor protein 63

1

2

Small-scale

0.457

High

556051

CADH1
Cadherin-1

1

1

Small-scale

0.445

High

764708

CTNB1
Catenin beta-1

1

4

Small-scale

0.445

High

778059

VGFR2
Vascular endothelial growth factor receptor 2

1

3

Small-scale

0.445

High

1051213

KPCZ
Protein kinase C zeta type

1

8

Small-scale

0.445

High

1091737

PDK1
[Pyruvate dehydrogenase

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025