Protein: RGRF2
Ras-specific guanine nucleotide-releasing factor 2 (Ras-GRF2) (Ras guanine nucleotide exchange factor 2)

Gene: RGRF2, RASGRF2
Organism: Homo sapiens
Interactions: 31
UniProt ID: O14827

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005516 - calmodulin binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

165463

FGD3
FYVE, RhoGEF and PH domain-containing protein 3

2

13

High-throughput

0.737

High

165464

DNMBP
Dynamin-binding protein

2

19

High-throughput

0.737

High

165450

RASK
GTPase KRas

1

20

Small-scale

0.647

High

165455

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.647

High

165456

RHOA
Transforming protein RhoA

1

20

High-throughput

0.647

High

165458

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.647

High

165448

RGRF2
Ras-specific guanine nucleotide-releasing factor 2

1

10

High-throughput

0.618

High

165474

NOSIP
Nitric oxide synthase-interacting protein

2

0

High-throughput

0.547

High

165475

UTP11
Probable U3 small nucleolar RNA-associated protein 11

2

0

High-throughput

0.547

High

165469

AKTIP
AKT-interacting protein

1

1

High-throughput

0.541

High

165451

SNRPA
U1 small nuclear ribonucleoprotein A

2

6

High-throughput

0.521

High

165452

CSTF2
Cleavage stimulation factor subunit 2

2

5

High-throughput

0.521

High

165453

CTBP2
C-terminal-binding protein 2

2

3

High-throughput

0.521

High

165461

SF3A2
Splicing factor 3A subunit 2

2

4

High-throughput

0.521

High

165473

RLP24
Probable ribosome biogenesis protein RLP24

2

1

High-throughput

0.521

High

165467

PANK2
Pantothenate kinase 2, mitochondrial

1

0

High-throughput

0.493

High

165203

PSA7
Proteasome subunit alpha type-7

1

2

High-throughput

0.479

High

165457

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

5

High-throughput

0.479

High

165459

OS9
Protein OS-9

1

1

High-throughput

0.479

High

165462

ZYX
Zyxin

1

4

High-throughput

0.479

High

165465

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

165449

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

165460

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.458

High

165471

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.457

High

104841

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

165454

EPIPL
Epiplakin

1

14

High-throughput

0.437

High

165466

PSMA8
Proteasome subunit alpha-type 8

1

2

High-throughput

0.437

High

165468

CCD86
Coiled-coil domain-containing protein 86

1

1

High-throughput

0.437

High

165470

HM20A
High mobility group protein 20A

1

2

High-throughput

0.437

High

165472

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

1

High-throughput

0.437

High


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Last updated: 11Aug2025