Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: KCC2A (Q9UQM7)
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)
Gene: CAMK2A

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 12954639
Identification Methods anti tag coimmunoprecipitation, in-gel kinase assay
Interaction Type physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~Pkinase, CaMKII_AD~Pkinase, Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
and 4 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 648
Hs

1 478
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs

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Last updated: 15 Jul 2024