HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: BCR (P11274)
Breakpoint cluster region protein (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-26)
Gene: BCR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37682707
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP, Ras~RhoGEF
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0030036 - actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 1271
+	Hs
		374559 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		ABR_HUMAN (419-1271): 0: 580: 66.47
+	Hs
		374702 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		ARHGI_HUMAN (105-1065): 4.16e-81: 294: 13.03
+	Hs
		374703 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		FGD6_HUMAN (199-905): 6.25e-78: 285: 16.03
+	Hs
		174241 RAB35_HUMAN (4-187): 1.26e-82: 244: 31.28		ARHGA_HUMAN (82-965): 8.19e-75: 275: 16.38
+	Hs
		375645 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		FGD6_HUMAN (199-905): 6.25e-78: 285: 16.03
+	Hs
		269497 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		SRGP2_HUMAN (596-1242): 1.86e-74: 271: 14.16
+	Hs
		373901 RASN_HUMAN (1-189): 3.16e-85: 251: 85.19		RHG01_HUMAN (909-1254): 5.72e-72: 249: 17.70
+	Hs
		375408 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		FGD1_HUMAN (197-1017): 1.83e-72: 263: 14.43
+	Hs
		1061238 RAB35_HUMAN (4-187): 1.26e-82: 244: 31.28		RHG01_HUMAN (909-1254): 5.72e-72: 249: 17.70
+	Hs
		374620 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		ITSN1_HUMAN (497-766): 5.26e-62: 235: 24.15
+	Hs
		375453 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		RHG01_HUMAN (909-1254): 5.72e-72: 249: 17.70
+	Hs
		1144919 RAB35_HUMAN (4-187): 1.26e-82: 244: 31.28		ITSN1_HUMAN (497-766): 5.26e-62: 235: 24.15
+	Hs
		375552 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		ITSN1_HUMAN (497-766): 5.26e-62: 235: 24.15
+	Hs
		299547 RAB35_HUMAN (4-187): 1.26e-82: 244: 31.28		TRIO_HUMAN (487-1035): 1.08e-52: 206: 11.47
+	Hs
		299501 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		TRIO_HUMAN (487-1035): 1.08e-52: 206: 11.47
+	Hs
		374664 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		RHG21_HUMAN (1049-1216): 3.07e-23: 109: 40.00
+	Hs
		1144945 RAB35_HUMAN (4-187): 1.26e-82: 244: 31.28		RHG21_HUMAN (1049-1216): 3.07e-23: 109: 40.00
+	Hs
		374611 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		RBP1_HUMAN (1051-1211): 5.01e-20: 98.2: 34.55
+	Hs
		375594 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		RHG21_HUMAN (1049-1216): 3.07e-23: 109: 40.00
+	Hs
		375540 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		RBP1_HUMAN (1051-1211): 5.01e-20: 98.2: 34.55