HitPredict

Interactor 1: RPB1 (P04050)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit 1) (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (RNA polymerase II subunit B220)
Gene: RPO21

Interactor 2: RPB9 (P27999)
DNA-directed RNA polymerase II subunit RPB9 (RNA polymerase II subunit B9) (B12.6) (DNA-directed RNA polymerase II 14.2 kDa polypeptide) (DNA-directed RNA polymerase II subunit 9)
Gene: RPB9

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.980

The method score is based on:

Property Details
Experiments 10784442, 10393904, 11805826, 15610738, 16554755, 26787877, 33226341, 37968396, 20494970, 12697831, 10788499, 16429126, 25340856
Identification Methods x-ray crystallography, two hybrid, tandem affinity purification, affinity chromatography technology, biochemical
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb1_2~TFIIS_C, RNA_pol_Rpb1_3~TFIIS_C, RNA_pol_Rpb1_4~TFIIS_C, RNA_POL_M_15KD~RNA_pol_Rpb1_5, RNA_pol_Rpb1_5~TFIIS_C
Common GO terms GO:0001172 - RNA-templated transcription
GO:0005634 - nucleus
GO:0005665 - RNA polymerase II, core complex
GO:0006366 - transcription by RNA polymerase II
GO:0006367 - transcription initiation at RNA polymerase II promoter
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1733
Sc

1 122
+ Dm
+ Sc
+ Sp
+ Sc
+ Hs
+ Sc
+ Hs
+ Hs
+ At
+ At
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Bt
+ Hs
+ Hs

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Last updated: 15 Jul 2024