Interactor 1: IGF2 (P01344)
Insulin-like growth factor 2 (Insulin-like growth factor II) (IGF-II) (Somatomedin-A) (T3M-11-derived growth factor) [Cleaved into: Insulin-like growth factor II Ala-25 Del; Preptin]
Gene: IGF2
Interactor 2: IBP4 (P22692)
Insulin-like growth factor-binding protein 4 (IBP-4) (IGF-binding protein 4) (IGFBP-4)
Gene: IGFBP4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.72 | 1.00 | 0.849 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9722589, 33961781, unassigned1913 |
| Identification Methods | pull down, affinity chromatography technology, split luciferase complementation, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IGFBP~Insulin, Insulin~Thyroglobulin_1 |
| Common GO terms | GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0043410 - positive regulation of MAPK cascade |
| Homologous interactions | 10 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
