Protein: IGF1
Insulin-like growth factor 1 (Insulin-like growth factor I) (IGF-I) (Mechano growth factor) (MGF) (Somatomedin-C)

Gene: IGF1
Organism: Homo sapiens
Interactions: 24
UniProt ID: P05019

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0001649 - osteoblast differentiation
GO:0001775 - cell activation
GO:0001837 - epithelial to mesenchymal transition
GO:0001974 - blood vessel remodeling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

420272

IBP3
Insulin-like growth factor-binding protein 3

7

10

Small-scale

0.963

High

420274

IBP4
Insulin-like growth factor-binding protein 4

4

10

Small-scale

0.909

High

420269

IGF1R
Insulin-like growth factor 1 receptor

3

3

Small-scale

0.861

High

420275

IBP5
Insulin-like growth factor-binding protein 5

2

10

Small-scale

0.778

High

420282

IBP7
Insulin-like growth factor-binding protein 7

2

1

Small-scale

0.778

High

420270

IBP1
Insulin-like growth factor-binding protein 1

1

12

Small-scale

0.647

High

420271

IDE
Insulin-degrading enzyme

1

2

Small-scale

0.647

High

420277

CCN3
CCN family member 3

1

1

Small-scale

0.647

High

420268

INSR
Insulin receptor

1

3

Small-scale

0.618

High

420273

IBP2
Insulin-like growth factor-binding protein 2

1

10

Small-scale

0.575

High

390842

TRFE
Serotransferrin

1

1

Small-scale

0.501

High

420278

E2F1
Transcription factor E2F1

1

0

Small-scale

0.460

High

420279

SOX4
Transcription factor SOX-4

1

0

Small-scale

0.460

High

420284

IGSF1
Immunoglobulin superfamily member 1

1

0

Small-scale

0.460

High

193172

SOCS1
Suppressor of cytokine signaling 1

1

0

Small-scale

0.458

High

420276

ALS
Insulin-like growth factor-binding protein complex acid labile subunit

1

0

Small-scale

0.458

High

420283

ZDH23
Palmitoyltransferase ZDHHC23

1

1

Small-scale

0.437

High

420280

MKRN3
E3 ubiquitin-protein ligase makorin-3

2

0

High-throughput

0.316

High

420281

MESD
LRP chaperone MESD

2

0

High-throughput

0.316

High

420285

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

0

High-throughput

0.316

High

420286

BANP
Protein BANP

2

0

High-throughput

0.316

High

420287

ENKD1
Enkurin domain-containing protein 1

2

0

High-throughput

0.316

High

420289

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.269

Low

420288

ZDH18
Palmitoyltransferase ZDHHC18

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025