HitPredict

Interactor 1: IL1B (P01584)
Interleukin-1 beta (IL-1 beta) (Catabolin)
Gene: IL1B

Interactor 2: REL (Q04864)
Proto-oncogene c-Rel
Gene: REL

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19122653
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006954 - inflammatory response GO:0043123 - positive regulation of canonical NF-kappaB signal transduction GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 269 Hs			1 619
+	Hs
		1049038 I36RA_HUMAN (121-265): 1.6e-55: 177: 28.67		REL_HUMAN (1-619): 0: 692: 100.00
+	Mm
		532188 IL1B_MOUSE (1-269): 1.81e-124: 356: 67.53		TF65_MOUSE (2-576): 2e-167: 490: 38.89
+	Hs
		378561 IL1B_HUMAN (1-269): 1.4e-131: 374: 100.00		TF65_HUMAN (2-576): 4.76e-158: 466: 37.89
+	Hs
		378545 IL1B_HUMAN (1-269): 1.4e-131: 374: 100.00		NFKB1_HUMAN (1-375): 2.01e-145: 447: 37.47
+	Hs
		378559 IL1B_HUMAN (1-269): 1.4e-131: 374: 100.00		RELB_HUMAN (2-479): 1.53e-143: 430: 35.04
+	Hs
		378487 IL1A_HUMAN (1-262): 3.97e-87: 262: 23.32		TF65_HUMAN (2-576): 4.76e-158: 466: 37.89
+	Hs
		615214 IL1RA_HUMAN (90-265): 1.56e-49: 163: 25.68		TF65_HUMAN (2-576): 4.76e-158: 466: 37.89