HitPredict

Interactor 1: IGKC (P01834)
Immunoglobulin kappa constant (Ig kappa chain C region) (Ig kappa chain C region AG) (Ig kappa chain C region CUM) (Ig kappa chain C region EU) (Ig kappa chain C region OU) (Ig kappa chain C region ROY) (Ig kappa chain C region TI)
Gene: IGKC

Interactor 2: B2MG (P61769)
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]
Gene: B2M

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	25480565, 22020283
Identification Methods	surface plasmon resonance
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1-set~C1-set
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 107 Hs			1 119
+	Hs
		409434 Q860B5_HUMAN (1-105): 1.51e-39: 135: 20.95		HLAA_HUMAN (2-116): 1.54e-47: 157: 22.41
+	Hs
		409212 HLAA_HUMAN (1-103): 2.11e-38: 133: 21.36		HLAA_HUMAN (2-116): 1.54e-47: 157: 22.41
+	Hs
		380213 HLAH_HUMAN (1-105): 2.08e-38: 133: 20.95		HLAC_HUMAN (2-117): 1.04e-46: 155: 19.66
+	Hs
		409232 HLAA_HUMAN (1-103): 2.11e-38: 133: 21.36		HLAC_HUMAN (2-117): 1.04e-46: 155: 19.66
+	Hs
		379822 HLAH_HUMAN (1-105): 2.08e-38: 133: 20.95		HLAB_HUMAN (2-117): 1.57e-44: 149: 19.66
+	Hs
		379830 HLAA_HUMAN (1-103): 2.11e-38: 133: 21.36		HLAB_HUMAN (2-117): 1.57e-44: 149: 19.66
+	Hs
		380217 HLAH_HUMAN (1-105): 2.08e-38: 133: 20.95		HLAG_HUMAN (2-116): 8.65e-45: 149: 22.41
+	Mm
		379811 HA1L_MOUSE (2-105): 1.23e-39: 136: 18.27		B2MG_MOUSE (1-119): 4.78e-44: 141: 68.07
+	Mm
		379812 HA11_MOUSE (2-105): 2.53e-39: 135: 18.27		B2MG_MOUSE (1-119): 4.78e-44: 141: 68.07
+	Hs
		380216 HLAH_HUMAN (1-105): 2.08e-38: 133: 20.95		HLAE_HUMAN (2-117): 4.68e-42: 143: 21.85
+	Hs
		380395 HLAA_HUMAN (1-103): 2.11e-38: 133: 21.36		DQA1_HUMAN (20-119): 4.1e-43: 143: 27.72
+	Hs
		409242 HLAA_HUMAN (1-103): 2.11e-38: 133: 21.36		HLAE_HUMAN (2-117): 4.68e-42: 143: 21.85
+	Mm
		379817 HA17_MOUSE (2-106): 5.03e-39: 134: 20.00		B2MG_MOUSE (1-119): 4.78e-44: 141: 68.07
+	Mm
		379813 HA12_MOUSE (2-106): 2.07e-38: 133: 20.00		B2MG_MOUSE (1-119): 4.78e-44: 141: 68.07
+	Rn
		450674 HA12_RAT (2-105): 2.71e-38: 133: 17.31		B2MG_RAT (1-119): 3.96e-44: 141: 69.75
+	Hs
		97102 HLAA_HUMAN (1-103): 2.11e-38: 133: 21.36		E9PMV2_HUMAN (20-115): 5.2e-43: 141: 30.93
+	Hs
		963532 Q95J06_HUMAN (1-105): 8.79e-40: 137: 20.95		B2MG_HUMAN (1-119): 1.65e-41: 134: 100.00
+	Hs
		380606 HLAA_HUMAN (1-103): 2.11e-38: 133: 21.36		DQB1_HUMAN (13-115): 4.06e-40: 135: 29.81
+	Hs
		963516 Q5S3G3_HUMAN (1-103): 2.87e-38: 133: 21.36		B2MG_HUMAN (1-119): 1.65e-41: 134: 100.00
+	Hs
		963517 Q5SUL5_HUMAN (1-103): 1.19e-38: 133: 21.36		B2MG_HUMAN (1-119): 1.65e-41: 134: 100.00