HitPredict

Interactor 1: IGKC (P01837)
Immunoglobulin kappa constant (Ig kappa chain C region MOPC 21)
Gene: IGKC

Interactor 2: IGG2B (P01867)
Immunoglobulin heavy constant gamma 2B (Ig gamma-2B chain C region)
Gene: Ighg2b

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	1749770, 8066444
Identification Methods	x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~C1-set
Common GO terms	GO:0005576 - extracellular region GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 107 Mm			1 404
+	Mm
		379151 IGKC_MOUSE (1-107): 2.03e-36: 121: 100.00		GCAM_MOUSE (1-404): 2.38e-113: 338: 78.47
+	Mm
		379154 IGKC_MOUSE (1-107): 2.03e-36: 121: 100.00		IGHG3_MOUSE (2-404): 1.45e-112: 336: 69.23
+	Mm
		379150 IGKC_MOUSE (1-107): 2.03e-36: 121: 100.00		GCAB_MOUSE (1-332): 1.6e-82: 257: 76.81
+	Mm
		379153 IGKC_MOUSE (1-107): 2.03e-36: 121: 100.00		IGHG1_MOUSE (1-334): 1.81e-81: 254: 62.87
+	Hs
		379789 HLAC_HUMAN (1-105): 3.41e-37: 130: 20.00		IGHD_HUMAN (2-379): 6.3e-63: 210: 23.22
+	Hs
		379788 HLAB_HUMAN (2-105): 1.38e-35: 125: 19.23		IGHD_HUMAN (2-379): 6.3e-63: 210: 23.22
+	Hs
		379609 IGLC1_HUMAN (4-107): 7.31e-38: 124: 41.35		IGHA1_HUMAN (2-379): 1.51e-50: 176: 27.78
+	Hs
		627557 DPA1_HUMAN (2-106): 3.87e-35: 122: 21.91		KIRR1_HUMAN (3-380): 5.06e-25: 109: 13.65
+	Hs
		85949 IGLL1_HUMAN (4-107): 3.8e-39: 131: 38.46		IGLL5_HUMAN (5-101): 4.4e-10: 61: 26.73
+	Hs
		85957 HLAF_HUMAN (1-105): 6.39e-38: 131: 20.00		IGLL5_HUMAN (5-101): 4.4e-10: 61: 26.73
+	Hs
		379208 IGLL1_HUMAN (4-107): 3.8e-39: 131: 38.46		IGHG1_HUMAN (1-131): 4.59e-09: 60: 25.37
+	Hs
		379276 Q8N355_HUMAN (4-107): 1.55e-38: 130: 40.39		IGHG1_HUMAN (1-131): 4.59e-09: 60: 25.37
+	Hs
		49203 IGLL5_HUMAN (4-107): 7.91e-39: 130: 41.35		IGLC7_HUMAN (4-92): 6.21e-10: 57.9: 27.96
+	Hs
		85945 IGLL5_HUMAN (4-107): 7.91e-39: 130: 41.35		IGLC6_HUMAN (4-92): 1.85e-09: 56.7: 25.81
+	Hs
		85946 IGLL5_HUMAN (4-107): 7.91e-39: 130: 41.35		IGLC3_HUMAN (4-101): 2.45e-09: 56.3: 28.43
+	Hs
		379198 IGLC1_HUMAN (4-107): 7.31e-38: 124: 41.35		IGHG1_HUMAN (1-131): 4.59e-09: 60: 25.37
+	Mm
		379157 IGHG1_MOUSE (5-103): 1.78e-36: 127: 29.00		LAC1_MOUSE (3-93): 9.73e-09: 54.4: 23.16