HitPredict

Interactor 1: LAC1 (P01843)
Ig lambda-1 chain C region
Gene: LAC1

Interactor 2: IGHG1 (P01868)
Ig gamma-1 chain C region secreted form
Gene: IGHG1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	1713710, 11812141
Identification Methods	x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~C1-set
Common GO terms	GO:0003823 - antigen binding GO:0016064 - immunoglobulin mediated immune response
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 105 Mm			1 324
+	Hs
		379276 Q8N355_HUMAN (1-105): 1.79e-40: 135: 71.43		IGHG1_HUMAN (1-322): 3.61e-77: 243: 60.06
+	Hs
		379208 IGLL1_HUMAN (1-105): 3.89e-39: 131: 70.48		IGHG1_HUMAN (1-322): 3.61e-77: 243: 60.06
+	Hs
		379198 IGLC1_HUMAN (1-105): 3.59e-40: 130: 71.43		IGHG1_HUMAN (1-322): 3.61e-77: 243: 60.06
+	Hs
		379057 IGKC_HUMAN (4-104): 2.56e-35: 118: 38.46		IGHG1_HUMAN (1-322): 3.61e-77: 243: 60.06
+	Hs
		379058 IGKC_HUMAN (4-104): 2.56e-35: 118: 38.46		IGHG4_HUMAN (1-316): 1.18e-73: 234: 60.19
+	Hs
		379059 IGKC_HUMAN (4-104): 2.56e-35: 118: 38.46		IGHM_HUMAN (2-323): 1.6e-26: 110: 22.09
+	Hs
		379609 IGLC1_HUMAN (1-105): 3.59e-40: 130: 71.43		IGHA1_HUMAN (6-239): 3.86e-18: 86.1: 23.46
+	Hs
		379789 HLAC_HUMAN (1-105): 5.85e-41: 140: 24.76		IGHD_HUMAN (3-242): 2e-11: 66.5: 18.95
+	Hs
		607393 HLAG_HUMAN (1-105): 1.67e-40: 138: 22.86		CADM4_HUMAN (6-102): 4.23e-12: 68.4: 19.39
+	Hs
		379788 HLAB_HUMAN (1-105): 3.62e-39: 135: 22.86		IGHD_HUMAN (3-242): 2e-11: 66.5: 18.95
+	Hs
		85957 HLAF_HUMAN (1-104): 9.78e-42: 141: 23.08		IGLL5_HUMAN (6-103): 5.36e-10: 60.2: 28.43
+	Hs
		85949 IGLL5_HUMAN (1-105): 1.2e-40: 135: 71.43		IGLL1_HUMAN (6-103): 3.2e-09: 57.9: 29.41
+	Hs
		49203 IGLL5_HUMAN (1-105): 1.2e-40: 135: 71.43		IGLC7_HUMAN (5-103): 1.28e-09: 56.7: 30.10
+	Hs
		85945 IGLL5_HUMAN (1-105): 1.2e-40: 135: 71.43		IGLC6_HUMAN (5-103): 3e-09: 55.6: 28.16
+	Hs
		85946 IGLL5_HUMAN (1-105): 1.2e-40: 135: 71.43		IGLC3_HUMAN (5-103): 8.49e-09: 54.4: 30.10
+	Mm
		634941 IGLL1_MOUSE (1-105): 2.23e-38: 129: 70.48		IGLL1_MOUSE (4-103): 2.29e-09: 58.3: 26.92