HitPredict

Interactor 1: HA1B (P01901)
H-2 class I histocompatibility antigen, K-B alpha chain (H-2K(B))
Gene: H2-K1

Interactor 2: LIRB3 (P97484)
Paired immunoglobulin-like receptor B (PIR-B) (Cell-surface glycoprotein p91) (Leukocyte immunoglobulin-like receptor subfamily B member 3) (LIR-3) (Leukocyte immunoglobulin-like receptor 3)
Gene: Pirb

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.80	0.687

Property	Details
Experiments	18787130, 19684158
Identification Methods	surface plasmon resonance, fluorescent resonance energy transfer
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	C1-set~ig, C1-set~Ig_2, MHC_I~ig, Ig_2~MHC_I
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 369 Mm			1 841
+	Hs
		1340138 Q95J06_HUMAN (1-360): 1e-169: 479: 65.57		LIRB1_HUMAN (1-443): 4.13e-75: 259: 36.16
+	Hs
		409456 HLAA_HUMAN (1-360): 5.38e-166: 469: 67.22		LIRB1_HUMAN (1-443): 4.13e-75: 259: 36.16
+	Hs
		1209906 Q5S3G3_HUMAN (1-360): 2.74e-165: 468: 66.39		LIRB1_HUMAN (1-443): 4.13e-75: 259: 36.16
+	Hs
		47606 HLAA_HUMAN (1-360): 5.38e-166: 469: 67.22		A0A8I5QEB2_HUMAN (419-823): 7.96e-70: 238: 24.14
+	Hs
		409302 HLAA_HUMAN (1-360): 5.38e-166: 469: 67.22		KI3L2_HUMAN (419-834): 1.12e-68: 236: 22.88
+	Hs
		850877 Q5S3G3_HUMAN (1-360): 2.74e-165: 468: 66.39		KI3L2_HUMAN (419-834): 1.12e-68: 236: 22.88
+	Hs
		1133831 Q95J06_HUMAN (1-360): 1e-169: 479: 65.57		KI3S1_HUMAN (23-241): 6.62e-61: 213: 30.36
+	Hs
		409383 HLAA_HUMAN (1-360): 5.38e-166: 469: 67.22		KI3S1_HUMAN (23-241): 6.62e-61: 213: 30.36
+	Hs
		1133828 Q5SUL5_HUMAN (1-360): 1.17e-162: 461: 64.46		KI3S1_HUMAN (23-241): 6.62e-61: 213: 30.36
+	Hs
		850828 Q5S3G3_HUMAN (1-360): 2.74e-165: 468: 66.39		KI2L3_HUMAN (518-832): 6.96e-43: 161: 21.56
+	Hs
		850827 Q5RIP0_HUMAN (1-359): 6.55e-159: 452: 64.09		KI2L3_HUMAN (518-832): 6.96e-43: 161: 21.56
+	Hs
		1325618 Q95J06_HUMAN (1-360): 1e-169: 479: 65.57		LIRB2_HUMAN (412-835): 5.44e-31: 131: 19.54
+	Hs
		850806 Q5RIP0_HUMAN (1-359): 6.55e-159: 452: 64.09		KI2L2_HUMAN (518-834): 2.39e-41: 156: 20.87
+	Hs
		409446 HLAA_HUMAN (1-360): 5.38e-166: 469: 67.22		LIRB2_HUMAN (412-835): 5.44e-31: 131: 19.54
+	Hs
		1209905 Q5S3G3_HUMAN (1-360): 2.74e-165: 468: 66.39		LIRB2_HUMAN (412-835): 5.44e-31: 131: 19.54
+	Hs
		850781 Q5RIP0_HUMAN (1-359): 6.55e-159: 452: 64.09		KI2L1_HUMAN (518-834): 4.23e-38: 147: 21.50
+	Hs
		850779 Q5D1W8_HUMAN (1-359): 9.03e-158: 449: 63.54		KI2L1_HUMAN (518-834): 4.23e-38: 147: 21.50
+	Hs
		850913 Q5S3G3_HUMAN (1-360): 2.74e-165: 468: 66.39		KI2S4_HUMAN (517-795): 1.47e-25: 109: 20.42
+	Hs
		409455 HLAA_HUMAN (1-360): 5.38e-166: 469: 67.22		LIRB4_HUMAN (23-137): 8.08e-18: 89.2: 29.17
+	Hs
		249080 HLAA_HUMAN (1-360): 5.38e-166: 469: 67.22		DSCAM_HUMAN (22-343): 7.75e-13: 74.7: 12.39