HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: RSC2 (Q06488)
Chromatin structure-remodeling complex subunit RSC2 (RSC complex subunit RSC2) (Remodel the structure of chromatin complex subunit 2)
Gene: RSC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.80	0.751

Property	Details
Experiments	16429126, 37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 131 Sc			1 889
+	Sc
		381643 H2B2_YEAST (1-131): 1.47e-45: 146: 96.95		RSC2_YEAST (1-889): 0: 724: 100.00
+	Hs
		1141161 H2B2F_HUMAN (7-128): 7.24e-47: 149: 70.97		BRD3_HUMAN (7-385): 5.44e-69: 245: 15.92
+	Hs
		1067403 H2B2E_HUMAN (7-128): 3.7e-46: 147: 70.97		EP300_HUMAN (4-191): 4.04e-32: 137: 18.75
+	Hs
		754818 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		EP300_HUMAN (4-191): 4.04e-32: 137: 18.75
+	Hs
		903383 H2B2E_HUMAN (7-128): 3.7e-46: 147: 70.97		SMCA4_HUMAN (9-122): 7.81e-29: 126: 29.92
+	Hs
		674183 H2B2E_HUMAN (7-128): 3.7e-46: 147: 70.97		BRD2_HUMAN (2-255): 7.8e-29: 125: 15.89
+	Hs
		674090 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		BRD2_HUMAN (2-255): 7.8e-29: 125: 15.89
+	Hs
		260026 H2B2E_HUMAN (7-128): 3.7e-46: 147: 70.97		BRD4_HUMAN (2-329): 6.26e-26: 117: 12.31
+	Hs
		260268 H2B1H_HUMAN (7-128): 3.91e-46: 147: 70.97		BRD4_HUMAN (2-329): 6.26e-26: 117: 12.31
+	Hs
		259521 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		BRD4_HUMAN (2-329): 6.26e-26: 117: 12.31
+	Hs
		1163225 H2B2E_HUMAN (7-128): 3.7e-46: 147: 70.97		BRD7_HUMAN (2-234): 2.98e-24: 110: 13.08
+	Hs
		1372315 H2B1H_HUMAN (7-128): 3.91e-46: 147: 70.97		ASH1L_HUMAN (6-170): 3.38e-20: 99.3: 19.76
+	Hs
		1163092 H2B2E_HUMAN (7-128): 3.7e-46: 147: 70.97		PHIP_HUMAN (19-253): 2.28e-19: 96.3: 14.05
+	Hs
		1163025 H2B2E_HUMAN (7-128): 3.7e-46: 147: 70.97		PB1_HUMAN (3-297): 8.33e-19: 94.4: 12.17
+	Sc
		381483 H2B2_YEAST (1-131): 1.47e-45: 146: 96.95		BDF1_YEAST (26-219): 5.3e-19: 94.4: 12.63
+	Hs
		1163285 H2B2E_HUMAN (7-128): 3.7e-46: 147: 70.97		ZMYD8_HUMAN (11-121): 1.28e-15: 84: 20.18
+	Sc
		381576 H2B2_YEAST (1-131): 1.47e-45: 146: 96.95		RSC1_YEAST (4-149): 3.77e-12: 72.4: 17.57
+	Hs
		180833 H2B2E_HUMAN (7-128): 3.7e-46: 147: 70.97		TIF1A_HUMAN (47-132): 1.22e-11: 71: 32.22
+	Sc
		381455 H2B2_YEAST (1-131): 1.47e-45: 146: 96.95		STH1_YEAST (275-377): 2.5e-11: 69.8: 24.27
+	Sc
		381603 H2B2_YEAST (1-131): 1.47e-45: 146: 96.95		RSC4_YEAST (34-128): 1.92e-10: 66.7: 27.84