HitPredict

Interactor 1: H3 (P02299)
Histone H3
Gene: H3, His3;

Interactor 2: PC (P26017)
Polycomb group protein Pc (Protein polycomb)
Gene: PC

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	1.00	0.935

Property	Details
Experiments	12408863, 23320494, 12351676, 17210640, 12897054, unassigned4
Identification Methods	affinity chromatography technology, far western blotting, fluorescence polarization spectroscopy, x-ray crystallography, experimental interaction detection
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Chromo~Histone
Common GO terms	GO:0000785 - chromatin GO:0005700 - polytene chromosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Dm			1 390
+	Hs
		338804 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CBX6_HUMAN (17-378): 1.72e-66: 218: 20.46
+	Hs
		338846 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		CBX6_HUMAN (17-378): 1.72e-66: 218: 20.46
+	Hs
		998829 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CBX8_HUMAN (17-380): 4.13e-60: 201: 20.15
+	Hs
		998961 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CDYL_HUMAN (5-282): 8.7e-54: 189: 15.73
+	Hs
		129710 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CBX4_HUMAN (17-338): 4.29e-46: 167: 18.53
+	Hs
		129736 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		CBX4_HUMAN (17-338): 4.29e-46: 167: 18.53
+	Hs
		998548 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CDYL2_HUMAN (24-218): 8.07e-41: 152: 16.74
+	Hs
		998807 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		SUV92_HUMAN (24-166): 2.56e-41: 152: 19.18
+	Hs
		998322 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CBX2_HUMAN (16-333): 1.48e-38: 146: 16.52
+	Hs
		351379 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CBX7_HUMAN (17-237): 2.27e-39: 142: 20.18
+	Hs
		351386 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		CBX7_HUMAN (17-237): 2.27e-39: 142: 20.18
+	Hs
		216410 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		SUV91_HUMAN (26-165): 4.79e-32: 127: 13.99
+	Hs
		998722 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		MPP8_HUMAN (18-333): 1.86e-27: 116: 12.97
+	Hs
		998274 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CBX3_HUMAN (6-87): 1.2e-28: 112: 30.49
+	Hs
		1097314 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		CBX3_HUMAN (6-87): 1.2e-28: 112: 30.49
+	Hs
		853220 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CBX5_HUMAN (7-124): 8.42e-26: 104: 23.73
+	Hs
		853278 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		CBX5_HUMAN (7-124): 8.42e-26: 104: 23.73
+	Hs
		998210 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CBX1_HUMAN (32-120): 1.62e-23: 98.5: 31.46
+	Mm
		999019 H31_MOUSE (1-136): 3.1e-62: 188: 99.27		CBX1_MOUSE (32-120): 1.62e-23: 98.5: 31.46
+	Hs
		1014111 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		CBX1_HUMAN (32-120): 1.62e-23: 98.5: 31.46