Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1
Interactor 2: CENPA (P36012)
Histone H3-like centromeric protein CSE4 (CENP-A homolog) (CENPA homolog) (Chromosome segregation protein 4)
Gene: CSE4
Species: Saccharomyces cerevisiae S288C
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.972 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 30381395, 17634282, 28980861, 31112132, 19782029, 37506202, 31578520, 38038247, 38565139, 21070971, 21816344, 22199229 |
| Identification Methods | x-ray crystallography, two hybrid, affinity chromatography technology, biochemical, pull down |
| Interaction Type | association, direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CENP-T_C~Histone |
| Common GO terms | GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
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| + | Kl |   |
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| + | Ce | |
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| + | Hs | |
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| + | Mm | |
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| + | Hs | |
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| + | Xl | |
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| + | Xl | |
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| + | Hs | |
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| + | Hs | |
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| + | Mm | |
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| + | Mm | |
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| + | Ce | |
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| + | Hs | |
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| + | Sc | |
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| + | Sp | |
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| + | Hs | |
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| + | Hs | |
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
