Interactor 1: IF4G1 (Q04637)
Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220)
Gene: EIF4G1

Interactor 2: IF4G1 (Q04637)
Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G 1) (eIF-4G1) (p220)
Gene: EIF4G1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.806

The method score is based on:

Property Details
Experiments 24248602, 16698552
Identification Methods affinity chromatography technology, x-ray crystallography, coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains MA3~MA3, MIF4G~MIF4G, W2~W2
Common GO terms GO:0001662 - behavioral fear response
GO:0002191 - cap-dependent translational initiation
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0003743 - translation initiation factor activity
and 36 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1599
Hs

1 1599
+ Hs
+ Hs
+ Mm
+ Hs
+ Pf
+ Pf
+ Sc
+ Sc
+ Dm

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Last updated: 15 Jul 2024