HitPredict

Interactor 1: H4 (P62799)
Histone H4
Gene: H4

Interactor 2: H32 (P84233)
Histone H3.2
Gene: H32

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.799

Property	Details
Experiments	32631887, 17293877
Identification Methods	pull down, static light scattering, molecular sieving
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CENP-T_C~Histone
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 103 Xl			1 136
+	Hs
		979480 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		H31_HUMAN (1-136): 3.1e-62: 188: 99.27
+	Mm
		980639 H4_MOUSE (1-103): 1.39e-48: 151: 100.00		H31_MOUSE (1-136): 3.1e-62: 188: 99.27
+	Xl
		979443 H4_XENLA (1-103): 1.39e-48: 151: 100.00		Q92133_XENLA (1-136): 2.93e-61: 186: 99.27
+	Hs
		979499 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		H33_HUMAN (1-136): 2.57e-61: 186: 97.06
+	Hs
		979740 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		H31T_HUMAN (1-136): 1.38e-61: 186: 96.32
+	Mm
		980643 H4_MOUSE (1-103): 1.39e-48: 151: 100.00		H33_MOUSE (1-136): 2.57e-61: 186: 97.06
+	Hs
		979874 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		H32_HUMAN (1-136): 6.24e-61: 185: 100.00
+	Mm
		980642 H4_MOUSE (1-103): 1.39e-48: 151: 100.00		H32_MOUSE (1-136): 6.24e-61: 185: 100.00
+	Ce
		477116 H4_CAEEL (1-103): 1.42e-48: 151: 99.03		H3_CAEEL (1-136): 1.34e-60: 184: 97.06
+	Hs
		979838 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		H3C_HUMAN (1-136): 5.27e-58: 177: 94.12
+	Sp
		480419 H4_SCHPO (18-103): 4.89e-42: 135: 89.54		H31_SCHPO (1-136): 3.44e-59: 181: 91.91
+	Hs
		1258924 H4G_HUMAN (1-98): 1.04e-38: 126: 84.69		H32_HUMAN (1-136): 6.24e-61: 185: 100.00
+	Sc
		382276 H4_YEAST (18-103): 6.16e-41: 132: 90.70		H3_YEAST (1-136): 1.23e-55: 171: 88.97
+	Ce
		759327 H4_CAEEL (1-103): 1.42e-48: 151: 99.03		HCP3L_CAEEL (11-131): 3.79e-44: 146: 45.16
+	Hs
		883497 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		CENPA_HUMAN (9-133): 2.87e-44: 143: 50.00
+	Kl
		1231316 Q6CMU6_KLULA (18-103): 9.45e-42: 134: 91.86		CENPA_KLULA (14-134): 1.15e-43: 143: 54.84
+	Sc
		382025 H4_YEAST (18-103): 6.16e-41: 132: 90.70		CENPA_YEAST (18-134): 2.58e-43: 143: 56.67