Interactor 1: CENPA (P49450)
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)
Gene: CENPA
Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.965 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 34079125, 15009096, 20080577, 16622419, 24530302, 20739937, 26167883, 19410544, 21478274 |
| Identification Methods | proximity labelling technology, biochemical, affinity chromatography technology, x-ray crystallography, x ray scattering, molecular sieving, tandem affinity purification |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CENP-T_C~Histone |
| Common GO terms | GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0030527 - structural constituent of chromatin and 3 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
