Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.992

The method score is based on:

Property Details
Experiments 25533843, 27248496, 30804502, 37071682, 37075063, 35575683, 38334954, 39358380, 8598932, 14578449, 26527279, 28514442, 22828868, 29568061, 34079125, 33961781, 18571423, 35772497, 34349018, 35235311 and 10 others

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Identification Methods affinity chromatography technology, cross-linking study, pull down, biochemical, proximity labelling technology, molecular sieving, dynamic light scattering, x ray scattering, mammalian protein protein interaction trap, anti tag coimmunoprecipitation and 1 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CENP-T_C~Histone
Common GO terms GO:0000786 - nucleosome
GO:0003677 - DNA binding
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 8 others

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Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 103
Hs

1 136
+ Mm
+ Hs
+ Xl
+ Xl
+ Hs
+ Hs
+ Mm
+ Mm
+ Ce
+ Hs
+ Sp
+ Hs
+ Sc
+ Ce
+ Hs
+ Sc
+ Kl

Service provided by Combinatics, Japan

Last updated: 11Aug2025