Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.990

The method score is based on:

Property Details
Experiments 22343720, 10436015, 8017102, 11694505, 16554755, 18467557, 32253346, 37968396, 31851481, 15516689, 22199229, 9372928, 11412995, 27601672, 32631887, 31269447, 19782027, 28104838, 38925115, 21749977 and 5 others

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Identification Methods anti bait coimmunoprecipitation, coimmunoprecipitation, affinity chromatography technology, protein complementation assay, cross-linking study, biochemical, pull down, fluorescent resonance energy transfer, tandem affinity purification, dihydrofolate reductase reconstruction and 1 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CENP-T_C~Histone
Common GO terms GO:0000500 - RNA polymerase I upstream activating factor complex
GO:0000786 - nucleosome
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0006325 - chromatin organization
and 5 others

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Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 103
Sc

1 136
+ Hs
+ Mm
+ Hs
+ Mm
+ Xl
+ Ce
+ Xl
+ Hs
+ Hs
+ Mm
+ Sp
+ Hs
+ Hs
+ Sc
+ Hs
+ Ce
+ Kl

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Last updated: 11Aug2025