HitPredict

Interactor 1: H3 (P08898)
Histone H3
Gene: his-2

Interactor 2: H4 (P62784)
Histone H4
Gene: his-1

Species: Caenorhabditis elegans

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26952210
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CENP-T_C~Histone
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 136 Ce			1 103
+	Hs
		979480 H31_HUMAN (1-136): 8.91e-63: 189: 97.79		H4_HUMAN (1-103): 3.13e-48: 150: 99.03
+	Mm
		980639 H31_MOUSE (1-136): 8.91e-63: 189: 97.79		H4_MOUSE (1-103): 3.13e-48: 150: 99.03
+	Hs
		979740 H31T_HUMAN (1-136): 4.37e-62: 188: 94.85		H4_HUMAN (1-103): 3.13e-48: 150: 99.03
+	Xl
		979443 Q92133_XENLA (1-136): 1.11e-61: 187: 96.32		H4_XENLA (1-103): 3.13e-48: 150: 99.03
+	Hs
		979499 H33_HUMAN (1-136): 9.5e-62: 187: 94.12		H4_HUMAN (1-103): 3.13e-48: 150: 99.03
+	Mm
		980643 H33_MOUSE (1-136): 9.5e-62: 187: 94.12		H4_MOUSE (1-103): 3.13e-48: 150: 99.03
+	Xl
		979441 H32_XENLA (1-136): 1.96e-61: 186: 97.06		H4_XENLA (1-103): 3.13e-48: 150: 99.03
+	Hs
		979874 H32_HUMAN (1-136): 1.96e-61: 186: 97.06		H4_HUMAN (1-103): 3.13e-48: 150: 99.03
+	Mm
		980642 H32_MOUSE (1-136): 1.96e-61: 186: 97.06		H4_MOUSE (1-103): 3.13e-48: 150: 99.03
+	Hs
		979838 H3C_HUMAN (1-136): 4.8e-59: 180: 91.18		H4_HUMAN (1-103): 3.13e-48: 150: 99.03
+	Sp
		480419 H31_SCHPO (1-136): 1.23e-59: 182: 89.71		H4_SCHPO (18-103): 1.08e-41: 133: 88.37
+	Hs
		1258924 H32_HUMAN (1-136): 1.96e-61: 186: 97.06		H4G_HUMAN (1-98): 2.87e-38: 125: 83.67
+	Sc
		382276 H3_YEAST (1-136): 4.08e-56: 173: 86.77		H4_YEAST (18-103): 1.48e-40: 131: 89.54
+	Ce
		759327 HCP3L_CAEEL (11-131): 2.6e-44: 147: 44.36		H4_CAEEL (1-103): 7.78e-49: 152: 100.00
+	Hs
		883497 CENPA_HUMAN (9-133): 1.12e-44: 144: 48.49		H4_HUMAN (1-103): 3.13e-48: 150: 99.03
+	Kl
		1231316 CENPA_KLULA (14-134): 7.3e-44: 143: 54.84		Q6CMU6_KLULA (18-103): 2.25e-41: 133: 90.70
+	Sc
		382025 CENPA_YEAST (18-134): 1.04e-43: 144: 55.00		H4_YEAST (18-103): 1.48e-40: 131: 89.54