HitPredict

Interactor 1: P53 (P02340)
Cellular tumor antigen p53 (Tumor suppressor p53)
Gene: Tp53

Interactor 2: BCL2 (P10417)
Apoptosis regulator Bcl-2
Gene: BCL2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 30683842
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~P53, BH4~P53
Common GO terms GO:0001836 - release of cytochrome c from mitochondria
GO:0002020 - protease binding
GO:0002326 - B cell lineage commitment
GO:0002360 - T cell lineage commitment
GO:0002931 - response to ischemia
and 25 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 390
Mm

1 236
+ Hs
+ Mm
+ Hs
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025