Interactor 1: CO1A1 (P02452)
Collagen alpha-1(I) chain (Alpha-1 type I collagen)
Gene: COL1A1
Interactor 2: SMAD4 (Q13485)
Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4)
Gene: SMAD4
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 0.60 | 0.534 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19558215 |
| Identification Methods | electrophoretic mobility supershift assay, anti tag coimmunoprecipitation, nucleic acid uv cross-linking assay |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0001649 - osteoblast differentiation GO:0010718 - positive regulation of epithelial to mesenchymal transition GO:0045893 - positive regulation of DNA-templated transcription GO:0046872 - metal ion binding GO:0071333 - cellular response to glucose stimulus and 1 others more... |
| Homologous interactions | 16 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
