HitPredict

Interactor 1: CO2A1 (P02458)
Collagen alpha-1(II) chain (Alpha-1 type II collagen) [Cleaved into: Collagen alpha-1(II) chain; Chondrocalcin]
Gene: COL2A1

Interactor 2: KLH22 (Q53GT1)
Kelch-like protein 22
Gene: KLHL22

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	37788672
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1487 Hs			1 634
+	Hs
		384315 CO4A1_HUMAN (221-1302): 1.24e-102: 364: 35.87		KLH22_HUMAN (1-634): 2.13e-169: 499: 100.00
+	Hs
		384254 CO2A1_HUMAN (1-1487): 0: 786: 100.00		KEAP1_HUMAN (531-632): 3.49e-12: 71.4: 16.67
+	Hs
		438032 CO5A2_HUMAN (3-687): 9.92e-93: 332: 37.52		KLH22_HUMAN (1-634): 2.13e-169: 499: 100.00
+	Hs
		551740 COBA1_HUMAN (3-943): 6.17e-83: 303: 40.28		KLH22_HUMAN (1-634): 2.13e-169: 499: 100.00
+	Hs
		1199601 COMA1_HUMAN (6-967): 2.87e-67: 253: 36.38		KLH22_HUMAN (1-634): 2.13e-169: 499: 100.00
+	Hs
		465966 CO1A2_HUMAN (655-1302): 3.44e-66: 249: 38.97		KLH22_HUMAN (1-634): 2.13e-169: 499: 100.00
+	Hs
		384164 CO1A1_HUMAN (3-646): 7.23e-57: 219: 36.49		KLH22_HUMAN (1-634): 2.13e-169: 499: 100.00
+	Hs
		1165441 COOA1_HUMAN (4-388): 4.01e-51: 201: 34.81		KLH22_HUMAN (1-634): 2.13e-169: 499: 100.00
+	Hs
		384286 CO3A1_HUMAN (1-1487): 0: 583: 59.36		KLH12_HUMAN (529-631): 1.19e-13: 76: 13.59
+	Hs
		1036624 CO7A1_HUMAN (814-1303): 5.9e-36: 152: 33.82		KLH22_HUMAN (1-634): 2.13e-169: 499: 100.00
+	Hs
		438038 CO5A2_HUMAN (3-687): 9.92e-93: 332: 37.52		KLH15_HUMAN (29-603): 8.94e-82: 271: 30.54
+	Hs
		551746 COBA1_HUMAN (3-943): 6.17e-83: 303: 40.28		KLH15_HUMAN (29-603): 8.94e-82: 271: 30.54
+	Hs
		1058770 COGA1_HUMAN (3-334): 1.8e-12: 74.8: 26.36		KLH22_HUMAN (1-634): 2.13e-169: 499: 100.00
+	Hs
		635465 CO5A1_HUMAN (8-961): 3.39e-71: 266: 40.36		KLH15_HUMAN (29-603): 8.94e-82: 271: 30.54
+	Dm
		465881 CO4A1_DROME (3-777): 4.19e-111: 390: 35.25		Q7K0L2_DROME (493-632): 3.68e-22: 103: 16.43
+	Dm
		1264215 Q9VMV5_DROME (2-877): 1.05e-105: 374: 34.59		Q7K0L2_DROME (493-632): 3.68e-22: 103: 16.43
+	Hs
		384153 CO1A1_HUMAN (3-646): 7.23e-57: 219: 36.49		KEAP1_HUMAN (531-632): 3.49e-12: 71.4: 16.67
+	Hs
		1058774 COGA1_HUMAN (3-334): 1.8e-12: 74.8: 26.36		IPP_HUMAN (445-632): 8.83e-41: 158: 16.84
+	Hs
		551917 CO6A3_HUMAN (101-184): 2.67e-09: 64.3: 38.79		KLHL4_HUMAN (430-633): 8.46e-43: 166: 20.10
+	Hs
		1058769 COGA1_HUMAN (3-334): 1.8e-12: 74.8: 26.36		KLH12_HUMAN (529-631): 1.19e-13: 76: 13.59