HitPredict

Interactor 1: CFAD (P03953)
Complement factor D (EC 3.4.21.46) (28 kDa adipocyte protein) (Adipsin) (C3 convertase activator) (Properdin factor D)
Gene: Cfd

Interactor 2: FBLN7 (Q501P1)
Fibulin-7 (FIBL-7) (Protein TM14)
Gene: FBLN7

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30550785
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EGF~Trypsin, FXa_inhibition~Trypsin, Sushi~Trypsin
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 259 Mm			1 440
+	Mm
		399229 CFAD_MOUSE (1-259): 2.94e-111: 322: 100.00		FBLN4_MOUSE (123-440): 1.01e-43: 160: 24.37
+	Mm
		398140 CFAD_MOUSE (1-259): 2.94e-111: 322: 100.00		FBLN2_MOUSE (55-342): 6.46e-25: 109: 19.28
+	Mm
		99232 CFAD_MOUSE (1-259): 2.94e-111: 322: 100.00		F2Z4A3_MOUSE (6-133): 7.52e-24: 107: 10.85
+	Mm
		148141 CFAD_MOUSE (1-259): 2.94e-111: 322: 100.00		MATN2_MOUSE (4-278): 1.22e-23: 106: 13.31
+	Hs
		437618 HEPS_HUMAN (15-259): 1.79e-101: 303: 30.68		PROS_HUMAN (174-335): 3.44e-27: 116: 27.16
+	Hs
		1286950 TM11B_HUMAN (13-253): 4.24e-101: 302: 31.73		AGRE2_HUMAN (190-352): 4.61e-23: 104: 26.29
+	Mm
		398657 CFAD_MOUSE (1-259): 2.94e-111: 322: 100.00		FBLN3_MOUSE (120-384): 1.39e-12: 71.4: 16.51
+	Hs
		1286958 TM11B_HUMAN (13-253): 4.24e-101: 302: 31.73		JAG2_HUMAN (123-330): 1.03e-16: 84.8: 20.43
+	Mm
		398716 CFAD_MOUSE (1-259): 2.94e-111: 322: 100.00		LTBP1_MOUSE (230-345): 2.54e-10: 64.8: 29.92
+	Mm
		204901 CFAD_MOUSE (1-259): 2.94e-111: 322: 100.00		NOTC2_MOUSE (18-327): 7.73e-10: 63.3: 12.05
+	Mm
		399205 CFAD_MOUSE (1-259): 2.94e-111: 322: 100.00		SLIT2_MOUSE (99-222): 5.79e-09: 60.6: 19.05
+	Hs
		1448854 TMPS4_HUMAN (9-252): 5.36e-99: 297: 35.06		JAG2_HUMAN (123-330): 1.03e-16: 84.8: 20.43
+	Hs
		398001 KLKB1_HUMAN (3-256): 6.24e-103: 313: 30.30		FBN2_HUMAN (133-305): 3.71e-09: 61.2: 31.03
+	Hs
		1126026 TM11B_HUMAN (13-253): 4.24e-101: 302: 31.73		GAS6_HUMAN (205-305): 2.33e-10: 64.7: 37.62
+	Hs
		437665 HEPS_HUMAN (15-259): 1.79e-101: 303: 30.68		NOTC2_HUMAN (18-327): 8.01e-10: 63.3: 13.17
+	Hs
		1047609 TM11B_HUMAN (13-253): 4.24e-101: 302: 31.73		NOTC2_HUMAN (18-327): 8.01e-10: 63.3: 13.17
+	Hs
		437626 HEPS_HUMAN (15-259): 1.79e-101: 303: 30.68		FBLN1_HUMAN (62-341): 4.99e-09: 60.6: 18.59
+	Hs
		1127605 TMPS4_HUMAN (9-252): 5.36e-99: 297: 35.06		FAT1_HUMAN (314-402): 3.58e-10: 64.5: 16.85
+	Hs
		317591 TMPS4_HUMAN (9-252): 5.36e-99: 297: 35.06		SLIT2_HUMAN (99-222): 7.84e-10: 63.3: 17.46
+	Hs
		188755 TMPS2_HUMAN (9-256): 2.53e-97: 295: 29.34		SLIT2_HUMAN (99-222): 7.84e-10: 63.3: 17.46