HitPredict

Interactor 1: CFAD (P03953)
Complement factor D (EC 3.4.21.46) (28 kDa adipocyte protein) (Adipsin) (C3 convertase activator) (Properdin factor D)
Gene: Cfd

Interactor 2: Q9CPN9 (Q9CPN9)
trypsin (EC 3.4.21.4)
Gene: Prss3b

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30550785
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Trypsin~Trypsin
Common GO terms	GO:0004252 - serine-type endopeptidase activity
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 259 Mm			1 247
+	Mm
		398558 CFAD_MOUSE (1-259): 2.94e-111: 322: 100.00		Q792Z1_MOUSE (1-247): 4.61e-133: 376: 77.73
+	Mm
		399178 CFAD_MOUSE (1-259): 2.94e-111: 322: 100.00		TRY5_MOUSE (1-247): 1.39e-132: 375: 76.52
+	Hs
		457942 TRY1_HUMAN (1-257): 1.03e-111: 323: 31.92		TRY2_HUMAN (1-247): 7.89e-123: 350: 72.47
+	Hs
		458006 TRY3_HUMAN (9-257): 5.54e-106: 310: 32.14		TRY2_HUMAN (1-247): 7.89e-123: 350: 72.47
+	Hs
		1306937 TMPS6_HUMAN (17-253): 8.39e-100: 310: 31.98		KLK6_HUMAN (2-246): 2.79e-106: 308: 42.11
+	Hs
		239280 TM11D_HUMAN (18-253): 1.6e-102: 305: 31.33		TM11D_HUMAN (21-243): 3.68e-101: 301: 36.17
+	Hs
		240200 KLK8_HUMAN (7-255): 4.86e-100: 293: 35.55		KLK6_HUMAN (2-246): 2.79e-106: 308: 42.11
+	Hs
		1369666 KLK6_HUMAN (1-255): 9.32e-100: 292: 32.69		KLK6_HUMAN (2-246): 2.79e-106: 308: 42.11
+	Hs
		1160930 PRSS8_HUMAN (5-253): 2.19e-101: 300: 33.46		KLK15_HUMAN (15-247): 1.04e-101: 297: 44.08
+	Hs
		1160936 PRSS8_HUMAN (5-253): 2.19e-101: 300: 33.46		KLK5_HUMAN (11-247): 1.85e-98: 290: 46.06
+	Hs
		605123 CTRB1_HUMAN (3-256): 3.12e-99: 292: 29.74		CTRB2_HUMAN (1-247): 4e-99: 291: 37.79
+	Hs
		634761 GRAH_HUMAN (26-250): 3.25e-42: 145: 34.78		PRSS8_HUMAN (24-244): 2.87e-47: 161: 37.60