Protein: GRAH
Granzyme H (EC 3.4.21.-) (CCP-X) (Cathepsin G-like 2) (CTSGL2) (Cytotoxic T-lymphocyte proteinase) (Cytotoxic serine protease C) (CSP-C)

Gene: GRAH, GZMH
Organism: Homo sapiens
Interactions: 94
UniProt ID: P20718

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005615 - extracellular space
GO:0006508 - proteolysis
GO:0006915 - apoptotic process
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

211910

SPIT1
Kunitz-type protease inhibitor 1

1

15

High-throughput

0.691

High

634761

PRSS8
Prostasin

1

14

High-throughput

0.691

High

634807

ANTR1
Anthrax toxin receptor 1

1

9

High-throughput

0.618

High

344391

TBCD8
TBC1 domain family member 8

1

3

High-throughput

0.536

High

534622

BIP
Endoplasmic reticulum chaperone BiP

1

10

High-throughput

0.536

High

565553

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

4

High-throughput

0.536

High

634745

ERD22
ER lumen protein-retaining receptor 2

1

2

High-throughput

0.536

High

634748

EAA3
Excitatory amino acid transporter 3

1

1

High-throughput

0.536

High

634777

MIRO1
Mitochondrial Rho GTPase 1

1

5

High-throughput

0.536

High

634783

INT1
Integrator complex subunit 1

1

1

High-throughput

0.536

High

634786

NLGN2
Neuroligin-2

1

1

High-throughput

0.536

High

634789

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

5

High-throughput

0.536

High

634790

TM9S4
Transmembrane 9 superfamily member 4

1

4

High-throughput

0.536

High

634804

SPNS1
Protein spinster homolog 1

1

1

High-throughput

0.536

High

634808

SDF2L
Stromal cell-derived factor 2-like protein 1

1

5

High-throughput

0.536

High

634812

STK26
Serine/threonine-protein kinase 26

1

4

High-throughput

0.536

High

634815

DDX41
Probable ATP-dependent RNA helicase DDX41

1

2

High-throughput

0.536

High

634816

FBX2
F-box only protein 2

1

1

High-throughput

0.536

High

634821

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

4

High-throughput

0.536

High

634756

FAT1
Protocadherin Fat 1

1

16

High-throughput

0.514

High

634771

FAT4
Protocadherin Fat 4

1

20

High-throughput

0.514

High

634762

TYSD1
Peroxisomal leader peptide-processing protease

1

0

High-throughput

0.513

High

634770

INT5
Integrator complex subunit 5

1

0

High-throughput

0.513

High

634803

INT2
Integrator complex subunit 2

1

0

High-throughput

0.513

High

634806

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.513

High

634811

FANCI
Fanconi anemia group I protein

1

0

High-throughput

0.513

High

430984

LA
Lupus La protein

1

4

Small-scale

0.502

High

62208

DEN11
DENN domain-containing protein 11

1

2

High-throughput

0.489

High

231677

PEX1
Peroxisomal ATPase PEX1

1

3

High-throughput

0.489

High

318110

IPO13
Importin-13

1

4

High-throughput

0.489

High

407981

TBB4A
Tubulin beta-4A chain

1

20

High-throughput

0.489

High

457227

TBB5
Tubulin beta chain

1

20

High-throughput

0.489

High

634744

DCK
Deoxycytidine kinase

1

1

High-throughput

0.489

High

634746

GALNS
N-acetylgalactosamine-6-sulfatase

1

10

High-throughput

0.489

High

634749

MAGA2
Melanoma-associated antigen 2

1

2

High-throughput

0.489

High

634750

IRAK1
Interleukin-1 receptor-associated kinase 1

1

1

High-throughput

0.489

High

634751

AT12A
Potassium-transporting ATPase alpha chain 2

1

4

High-throughput

0.489

High

634753

TBA4A
Tubulin alpha-4A chain

1

20

High-throughput

0.489

High

634754

TBB3
Tubulin beta-3 chain

1

20

High-throughput

0.489

High

634755

RCN2
Reticulocalbin-2

1

4

High-throughput

0.489

High

634757

DPOD3
DNA polymerase delta subunit 3

1

1

High-throughput

0.489

High

634758

PON2
Serum paraoxonase/arylesterase 2

1

3

High-throughput

0.489

High

634759

UBE3C
Ubiquitin-protein ligase E3C

1

7

High-throughput

0.489

High

634760

SURF1
Surfeit locus protein 1

1

1

High-throughput

0.489

High

634763

TBB8
Tubulin beta-8 chain

1

20

High-throughput

0.489

High

634764

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

4

High-throughput

0.489

High

634766

HEAT6
HEAT repeat-containing protein 6

1

1

High-throughput

0.489

High

634767

TTC27
Tetratricopeptide repeat protein 27

1

5

High-throughput

0.489

High

634769

CNNM4
Metal transporter CNNM4

1

1

High-throughput

0.489

High

634773

TBA1A
Tubulin alpha-1A chain

1

20

High-throughput

0.489

High

634774

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

7

High-throughput

0.489

High

634776

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

1

4

High-throughput

0.489

High

634778

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

15

High-throughput

0.489

High

634784

VWDE
von Willebrand factor D and EGF domain-containing protein

1

14

High-throughput

0.489

High

634792

ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial

1

6

High-throughput

0.489

High

634795

PASK
PAS domain-containing serine/threonine-protein kinase

1

5

High-throughput

0.489

High

634797

TBA1C
Tubulin alpha-1C chain

1

20

High-throughput

0.489

High

634798

CSTN3
Calsyntenin-3

1

20

High-throughput

0.489

High

634799

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

4

High-throughput

0.489

High

634801

FACD2
Fanconi anemia group D2 protein

1

6

High-throughput

0.489

High

634810

PANK4
4'-phosphopantetheine phosphatase

1

1

High-throughput

0.489

High

634817

SARDH
Sarcosine dehydrogenase, mitochondrial

1

2

High-throughput

0.489

High

634822

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

1

4

High-throughput

0.489

High

634765

RN123
E3 ubiquitin-protein ligase RNF123

1

5

High-throughput

0.479

High

634747

CASP3
Caspase-3

1

12

Small-scale

0.445

High

634752

BID
BH3-interacting domain death agonist

1

2

Small-scale

0.445

High

634781

VPS52
Vacuolar protein sorting-associated protein 52 homolog

1

1

High-throughput

0.445

High

634794

PCD16
Protocadherin-16

1

17

High-throughput

0.445

High

634818

PCDGK
Protocadherin gamma-C3

1

1

High-throughput

0.445

High

634820

PCDBB
Protocadherin beta-11

1

3

High-throughput

0.445

High

240736

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.437

High

130825

DFFA
DNA fragmentation factor subunit alpha

1

3

Small-scale

0.407

High

239718

PCDH7
Protocadherin-7

1

20

High-throughput

0.407

High

547091

PYC
Pyruvate carboxylase, mitochondrial

1

6

High-throughput

0.407

High

634768

PDXD2
Putative pyridoxal-dependent decarboxylase domain-containing protein 2

1

2

High-throughput

0.407

High

634772

PCD23
Protocadherin-23

1

17

High-throughput

0.407

High

634775

MEX3D
RNA-binding protein MEX3D

1

2

High-throughput

0.407

High

634782

ARG28
Rho guanine nucleotide exchange factor 28

1

2

High-throughput

0.407

High

634788

CE192
Centrosomal protein of 192 kDa

1

1

High-throughput

0.407

High

634796

RUFY1
RUN and FYVE domain-containing protein 1

1

3

High-throughput

0.407

High

634800

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

2

High-throughput

0.407

High

634802

MFR1L
Mitochondrial fission regulator 1-like

1

1

High-throughput

0.407

High

634805

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

6

High-throughput

0.407

High

634819

DICER
Endoribonuclease Dicer

1

4

High-throughput

0.407

High

124232

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.279

Low

634779

TRM44
Probable tRNA

1

0

High-throughput

0.279

Low

634780

FCSK
L-fucose kinase

1

0

High-throughput

0.279

Low

634785

MROH1
Maestro heat-like repeat-containing protein family member 1

1

0

High-throughput

0.279

Low

634787

NUBPL
Iron-sulfur cluster transfer protein NUBPL

1

0

High-throughput

0.279

Low

634791

FGF13
Fibroblast growth factor 13

1

0

High-throughput

0.279

Low

634793

INT4
Integrator complex subunit 4

1

0

High-throughput

0.279

Low

634809

T11L1
T-complex protein 11-like protein 1

1

0

High-throughput

0.279

Low

634814

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.279

Low

634813

AASS
Alpha-aminoadipic semialdehyde synthase, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025