Interactor 1: TMPS6 (Q8IU80)
Transmembrane protease serine 6 (EC 3.4.21.-) (Matriptase-2)
Gene: TMPRSS6
Interactor 2: KLK6 (Q92876)
Kallikrein-6 (EC 3.4.21.-) (Neurosin) (Protease M) (SP59) (Serine protease 18) (Serine protease 9) (Zyme)
Gene: KLK6
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32814053 |
| Identification Methods | two hybrid array, two hybrid pooling approach, validated two hybrid |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ldl_recept_a~Trypsin, Trypsin~Trypsin |
| Common GO terms | GO:0004252 - serine-type endopeptidase activity GO:0005615 - extracellular space GO:0030574 - collagen catabolic process |
| Homologous interactions | 18 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
