HitPredict

Interactor 1: FGF1 (P05230)
Fibroblast growth factor 1 (FGF-1) (Acidic fibroblast growth factor) (aFGF) (Endothelial cell growth factor) (ECGF) (Heparin-binding growth factor 1) (HBGF-1)
Gene: FGF1

Interactor 2: GPC3 (P51654)
Glypican-3 (GTR2-2) (Intestinal protein OCI-5) (MXR7) [Cleaved into: Glypican-3 alpha subunit; Glypican-3 beta subunit]
Gene: GPC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0009653 - anatomical structure morphogenesis GO:0030324 - lung development GO:0050673 - epithelial cell proliferation
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 155 Hs			1 580
+	Hs
		447030 FGF2_HUMAN (1-154): 7.49e-63: 196: 54.14		GPC3_HUMAN (1-580): 0: 805: 100.00
+	Hs
		441819 FGF4_HUMAN (15-151): 3.89e-55: 174: 35.51		GPC3_HUMAN (1-580): 0: 805: 100.00
+	Hs
		399138 FGF1_HUMAN (1-155): 2.95e-74: 220: 100.00		GPC1_HUMAN (25-487): 0: 581: 23.24
+	Hs
		399165 FGF1_HUMAN (1-155): 2.95e-74: 220: 100.00		GPC6_HUMAN (31-501): 0: 575: 26.19
+	Hs
		266520 FGF1_HUMAN (1-155): 2.95e-74: 220: 100.00		GPC4_HUMAN (31-486): 0: 565: 24.41
+	Hs
		266523 FGF2_HUMAN (1-154): 7.49e-63: 196: 54.14		GPC4_HUMAN (31-486): 0: 565: 24.41
+	Hs
		441815 FGF4_HUMAN (15-151): 3.89e-55: 174: 35.51		GPC1_HUMAN (25-487): 0: 581: 23.24
+	Hs
		266522 FGF4_HUMAN (15-151): 3.89e-55: 174: 35.51		GPC4_HUMAN (31-486): 0: 565: 24.41