Protein: CMA1
Chymase (EC 3.4.21.39) (Alpha-chymase) (Mast cell protease I)

Gene: CMA1
Organism: Homo sapiens
Interactions: 64
UniProt ID: P23946

Gene Ontology (top 5):
GO:0002003 - angiotensin maturation
GO:0004175 - endopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

663544

FAT1
Protocadherin Fat 1

2

16

High-throughput

0.776

High

663556

CD109
CD109 antigen

2

8

High-throughput

0.776

High

287528

LRP6
Low-density lipoprotein receptor-related protein 6

1

16

High-throughput

0.691

High

625983

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

1

3

High-throughput

0.691

High

663564

SORL
Sortilin-related receptor

1

17

High-throughput

0.691

High

663581

LOXL2
Lysyl oxidase homolog 2

1

10

High-throughput

0.691

High

376478

LDLR
Low-density lipoprotein receptor

1

17

High-throughput

0.618

High

663547

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

6

High-throughput

0.618

High

663554

FAT4
Protocadherin Fat 4

1

20

High-throughput

0.618

High

663573

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

1

16

High-throughput

0.618

High

663574

CELR1
Cadherin EGF LAG seven-pass G-type receptor 1

1

20

High-throughput

0.618

High

663579

JAG2
Protein jagged-2

1

8

High-throughput

0.618

High

663543

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

2

5

High-throughput

0.601

High

663559

FRAS1
Extracellular matrix organizing protein FRAS1

2

20

High-throughput

0.601

High

296342

ATRN
Attractin

1

18

High-throughput

0.575

High

562698

BMP1
Bone morphogenetic protein 1

1

15

High-throughput

0.575

High

641296

PGS1
Biglycan

1

5

Small-scale

0.575

High

663562

SRB4D
Scavenger receptor cysteine-rich domain-containing group B protein

1

8

High-throughput

0.575

High

136595

MANBA
Beta-mannosidase

2

6

High-throughput

0.549

High

534647

BIP
Endoplasmic reticulum chaperone BiP

1

13

High-throughput

0.536

High

663538

GALNS
N-acetylgalactosamine-6-sulfatase

1

9

High-throughput

0.536

High

663541

DIAC
Di-N-acetylchitobiase

1

1

High-throughput

0.536

High

663546

PON2
Serum paraoxonase/arylesterase 2

1

3

High-throughput

0.536

High

663550

FREM2
FRAS1-related extracellular matrix protein 2

1

20

High-throughput

0.536

High

663560

VWDE
von Willebrand factor D and EGF domain-containing protein

1

15

High-throughput

0.536

High

663566

I17RA
Interleukin-17 receptor A

1

4

High-throughput

0.536

High

663578

ATS7
A disintegrin and metalloproteinase with thrombospondin motifs 7

1

20

High-throughput

0.536

High

440377

FYN
Tyrosine-protein kinase Fyn

1

0

Small-scale

0.500

High

62286

MTMRB
Myotubularin-related protein 11

1

1

High-throughput

0.489

High

164728

HS3S1
Heparan sulfate glucosamine 3-O-sulfotransferase 1

1

1

High-throughput

0.489

High

663537

ACHA5
Neuronal acetylcholine receptor subunit alpha-5

1

2

High-throughput

0.489

High

663542

DSC2
Desmocollin-2

1

7

High-throughput

0.489

High

663549

TBB8
Tubulin beta-8 chain

1

20

High-throughput

0.489

High

663551

GLT18
Polypeptide N-acetylgalactosaminyltransferase 18

1

15

High-throughput

0.489

High

663561

PCD20
Protocadherin-20

1

12

High-throughput

0.489

High

663563

AGRV1
Adhesion G-protein coupled receptor V1

1

20

High-throughput

0.489

High

663570

CSTN3
Calsyntenin-3

1

20

High-throughput

0.489

High

663571

TOR3A
Torsin-3A

1

13

High-throughput

0.489

High

378548

IL1B
Interleukin-1 beta

1

0

Small-scale

0.480

High

663558

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

8

Small-scale

0.479

High

441469

AGAL
Alpha-galactosidase A

1

3

High-throughput

0.445

High

449560

HEXA
Beta-hexosaminidase subunit alpha

1

2

High-throughput

0.445

High

465410

IGF1R
Insulin-like growth factor 1 receptor

1

12

High-throughput

0.445

High

481095

HMGB1
High mobility group protein B1

1

5

Small-scale

0.445

High

663539

HSP13
Heat shock 70 kDa protein 13

1

4

High-throughput

0.445

High

663540

ATS12
A disintegrin and metalloproteinase with thrombospondin motifs 12

1

20

High-throughput

0.445

High

663552

GASP3
G protein-coupled receptor associated sorting protein 3

1

6

High-throughput

0.445

High

663553

MOXD1
DBH-like monooxygenase protein 1

1

4

High-throughput

0.445

High

663568

PASK
PAS domain-containing serine/threonine-protein kinase

1

5

High-throughput

0.445

High

663569

SORT
Sortilin

1

3

High-throughput

0.445

High

663576

DKK3
Dickkopf-related protein 3

1

2

High-throughput

0.445

High

612873

EGR1
Early growth response protein 1

1

2

High-throughput

0.437

High

592621

ITB4
Integrin beta-4

1

7

High-throughput

0.407

High

663548

MA2A1
Alpha-mannosidase 2

1

9

High-throughput

0.407

High

663555

PCD23
Protocadherin-23

1

17

High-throughput

0.407

High

663557

GALT7
N-acetylgalactosaminyltransferase 7

1

15

High-throughput

0.407

High

663565

T106A
Transmembrane protein 106A

1

1

High-throughput

0.407

High

663567

PCD16
Protocadherin-16

1

17

High-throughput

0.407

High

663572

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

15

High-throughput

0.407

High

663575

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

8

High-throughput

0.407

High

663577

GNPTG
N-acetylglucosamine-1-phosphotransferase subunit gamma

1

2

High-throughput

0.407

High

663580

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

3

High-throughput

0.407

High

663582

PCDBB
Protocadherin beta-11

1

3

High-throughput

0.407

High

663545

RRS1
Ribosome biogenesis regulatory protein homolog

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025