HitPredict

Interactor 1: CFAD (P03953)
Complement factor D (EC 3.4.21.46) (28 kDa adipocyte protein) (Adipsin) (C3 convertase activator) (Properdin factor D)
Gene: Cfd

Interactor 2: ATS5 (Q9R001)
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAM-TS 5) (ADAM-TS5) (ADAMTS-5) (EC 3.4.24.-) (ADMP-2) (Aggrecanase-2) (Implantin)
Gene: Adamts5

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30550785
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0006508 - proteolysis
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 259 Mm			1 930
+	Mm
		398344 CFAD_MOUSE (1-259): 2.94e-111: 322: 100.00		ATS1_MOUSE (63-930): 0: 713: 41.98
+	Hs
		437821 HEPS_HUMAN (15-259): 1.79e-101: 303: 30.68		ATS1_HUMAN (37-930): 0: 732: 41.69
+	Hs
		189028 TMPS2_HUMAN (9-256): 2.53e-97: 295: 29.34		ATS1_HUMAN (37-930): 0: 732: 41.69
+	Hs
		628473 KLK2_HUMAN (1-256): 2.92e-99: 292: 32.59		ATS1_HUMAN (37-930): 0: 732: 41.69
+	Hs
		1105787 TMPS4_HUMAN (9-252): 5.36e-99: 297: 35.06		ADAM9_HUMAN (43-749): 4.3e-149: 463: 19.38
+	Hs
		1105813 TM11B_HUMAN (13-253): 4.24e-101: 302: 31.73		ADA15_HUMAN (40-740): 9.31e-117: 379: 20.46
+	Hs
		1105830 TMPS4_HUMAN (9-252): 5.36e-99: 297: 35.06		ADA15_HUMAN (40-740): 9.31e-117: 379: 20.46
+	Hs
		188879 TMPS2_HUMAN (9-256): 2.53e-97: 295: 29.34		ADA15_HUMAN (40-740): 9.31e-117: 379: 20.46
+	Hs
		1105779 KLK15_HUMAN (16-256): 4.27e-45: 153: 37.40		ADAM9_HUMAN (43-749): 4.3e-149: 463: 19.38
+	Hs
		1429269 KLK15_HUMAN (16-256): 4.27e-45: 153: 37.40		ADA19_HUMAN (36-749): 3.63e-131: 420: 18.53
+	Hs
		437659 HEPS_HUMAN (15-259): 1.79e-101: 303: 30.68		ATL3_HUMAN (568-904): 4.44e-37: 153: 30.26
+	Hs
		437719 HEPS_HUMAN (15-259): 1.79e-101: 303: 30.68		ATL2_HUMAN (570-808): 1.89e-34: 144: 37.45
+	Mm
		74697 CFAD_MOUSE (1-259): 2.94e-111: 322: 100.00		B2RXX5_MOUSE (442-683): 5.09e-09: 62.6: 15.50
+	Hs
		337271 TM11B_HUMAN (13-253): 4.24e-101: 302: 31.73		ATS2_HUMAN (418-683): 1.01e-11: 71.1: 16.54
+	Hs
		437657 HEPS_HUMAN (15-259): 1.79e-101: 303: 30.68		ATS12_HUMAN (440-706): 7.51e-10: 65.3: 15.19
+	Hs
		663578 CMA1_HUMAN (18-256): 4.72e-39: 137: 33.74		ATS7_HUMAN (422-634): 1.72e-10: 67.2: 18.69
+	Hs
		663540 CMA1_HUMAN (18-256): 4.72e-39: 137: 33.74		ATS12_HUMAN (440-706): 7.51e-10: 65.3: 15.19
+	Hs
		455669 KLK3_HUMAN (25-256): 3.05e-37: 133: 35.37		ATS7_HUMAN (422-634): 1.72e-10: 67.2: 18.69
+	Hs
		449598 KLK1_HUMAN (5-256): 4.83e-37: 133: 34.07		ATS12_HUMAN (440-706): 7.51e-10: 65.3: 15.19