Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1
Interactor 2: PGFRB (P09619)
Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
Gene: PDGFRB
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 2475255 |
| Identification Methods | pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C1_1~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~Pkinase, PK_Tyr_Ser-Thr~RBD |
| Common GO terms | GO:0004672 - protein kinase activity GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus and 3 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
