HitPredict

Interactor 1: JUN (P05412)
Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)
Gene: JUN

Interactor 2: MK01 (P28482)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: MAPK1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.709

The method score is based on:

Property Details
Experiments 11431474, 29225075, 10419510, 1922387, 25609649
Identification Methods affinity chromatography technology, enzymatic study, pull down, biochemical, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0034614 - cellular response to reactive oxygen species
GO:0071276 - cellular response to cadmium ion
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 331
Hs

1 360
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024