HitPredict

Interactor 1: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Interactor 2: ITA2 (P17301)
Integrin alpha-2 (CD49 antigen-like family member B) (Collagen receptor) (Platelet membrane glycoprotein Ia) (GPIa) (VLA-2 subunit alpha) (CD antigen CD49b)
Gene: ITGA2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.883

The method score is based on:

Property Details
Experiments 21947080, 8846021, 10397731, 14681217
Identification Methods affinity chromatography technology, biophysical, anti bait coimmunoprecipitation, lex-a dimerization assay
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Integrin_B_tail~VWA, FG-GAP~Integrin_beta
Common GO terms GO:0001618 - virus receptor activity
GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0007155 - cell adhesion
and 14 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024