HitPredict

Interactor 1: JUN (P05627)
Transcription factor Jun (AH119) (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (Jun A)
Gene: JUN

Interactor 2: NOS2 (P29477)
Nitric oxide synthase, inducible (EC 1.14.13.39) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (MAC-NOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2)
Gene: NOS2

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	19299558, 18586011, 17940019, 21331046
Identification Methods	anti tag coimmunoprecipitation, electrophoretic mobility supershift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0042127 - regulation of cell population proliferation GO:0043065 - positive regulation of apoptotic process
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 334 Mm			1 1144
+	Hs
		401512 JUN_HUMAN (1-334): 5.59e-99: 296: 94.61		NOS2_HUMAN (1-1144): 0: 1775: 80.78
+	Hs
		568068 JUND_HUMAN (5-334): 3.1e-58: 193: 47.95		NOS2_HUMAN (1-1144): 0: 1775: 80.78
+	Mm
		667788 CREB1_MOUSE (36-310): 1.31e-35: 133: 16.56		NOS2_MOUSE (1-1144): 0: 1808: 100.00