HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: ATD3C (Q5T2N8)
ATPase family AAA domain-containing protein 3C
Gene: ATAD3C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	21182203
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 411
+	Hs
		397051 ESR1_HUMAN (1-595): 0: 599: 100.00		ATD3A_HUMAN (3-411): 7.15e-95: 297: 79.95
+	Hs
		395817 ESR1_HUMAN (1-595): 0: 599: 100.00		PRS8_HUMAN (15-399): 1.18e-95: 294: 17.16
+	Hs
		395833 ESR1_HUMAN (1-595): 0: 599: 100.00		PRS10_HUMAN (4-396): 1.75e-95: 293: 15.97
+	Hs
		395651 ESR1_HUMAN (1-595): 0: 599: 100.00		PRS6B_HUMAN (5-398): 1.2e-92: 286: 13.73
+	Rn
		439605 ESR1_RAT (1-595): 0: 558: 88.17		PRS8_RAT (15-399): 1.18e-95: 294: 17.16
+	Hs
		1214738 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		ATD3B_HUMAN (3-411): 5.02e-99: 310: 80.69
+	Hs
		969007 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		PRS8_HUMAN (15-399): 1.18e-95: 294: 17.16
+	Hs
		975476 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		PRS10_HUMAN (4-396): 1.75e-95: 293: 15.97
+	Hs
		851385 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		PRS6B_HUMAN (5-398): 1.2e-92: 286: 13.73
+	Hs
		625794 RXRA_HUMAN (65-551): 4.57e-127: 383: 26.47		PRS8_HUMAN (15-399): 1.18e-95: 294: 17.16
+	Hs
		404122 GCR_HUMAN (5-557): 4.69e-109: 346: 22.51		ATD3B_HUMAN (3-411): 5.02e-99: 310: 80.69
+	Hs
		343283 ERR2_HUMAN (92-547): 4.32e-116: 354: 34.86		ATD3A_HUMAN (3-411): 7.15e-95: 297: 79.95
+	Hs
		968868 ERR3_HUMAN (91-547): 2.28e-116: 355: 33.77		PRS8_HUMAN (15-399): 1.18e-95: 294: 17.16
+	Hs
		404472 GCR_HUMAN (5-557): 4.69e-109: 346: 22.51		ATD3A_HUMAN (3-411): 7.15e-95: 297: 79.95
+	Hs
		533220 RARB_HUMAN (111-579): 7.66e-114: 349: 22.47		PRS8_HUMAN (15-399): 1.18e-95: 294: 17.16
+	Hs
		968898 NR1H3_HUMAN (99-548): 6.23e-112: 343: 20.49		PRS8_HUMAN (15-399): 1.18e-95: 294: 17.16
+	Hs
		968917 HNF4G_HUMAN (174-594): 3.45e-112: 343: 23.28		PRS8_HUMAN (15-399): 1.18e-95: 294: 17.16
+	Hs
		467779 MCR_HUMAN (21-554): 3.99e-103: 335: 22.01		PRS8_HUMAN (15-399): 1.18e-95: 294: 17.16
+	Hs
		652486 NR4A1_HUMAN (64-549): 2.82e-105: 331: 24.54		PRS8_HUMAN (15-399): 1.18e-95: 294: 17.16
+	Hs
		565515 RARG_HUMAN (111-574): 2.16e-103: 321: 23.52		PRS8_HUMAN (15-399): 1.18e-95: 294: 17.16