HitPredict

Interactor 1: JUN (P05627)
Transcription factor Jun (AH119) (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (Jun A)
Gene: JUN

Interactor 2: ATF4 (Q06507)
Cyclic AMP-dependent transcription factor ATF-4 (cAMP-dependent transcription factor ATF-4) (Activating transcription factor 4) (C/EBP-related ATF) (C/ATF) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2)
Gene: ATF4

Species: Mus musculus

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	1.00	0.743

The method score is based on:

Property	Details
Experiments	20211142, 1631061
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	bZIP_1~bZIP_1
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0003677 - DNA binding GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus and 9 others more... GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II GO:0006366 - transcription by RNA polymerase II GO:0032991 - protein-containing complex GO:0043525 - positive regulation of neuron apoptotic process GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1	334
Mm

1	349

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024