HitPredict

Interactor 1: K2C6B (P04259)
Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK-6B) (Keratin-6B) (K6B) (Type-II keratin Kb10)
Gene: KRT6B

Interactor 2: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 564 Hs			1 334
+	Hs
		551579 K2C3_HUMAN (135-479): 2.62e-179: 521: 80.40		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		777530 K22E_HUMAN (135-521): 1.88e-166: 489: 68.48		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		407499 K2C1_HUMAN (128-494): 1.64e-164: 484: 73.84		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		341827 K2C75_HUMAN (3-564): 6.72e-102: 320: 68.32		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		131346 K22E_HUMAN (135-521): 1.88e-166: 489: 68.48		EIF3F_HUMAN (44-328): 3.26e-64: 208: 14.48
+	Hs
		131281 K2C1_HUMAN (128-494): 1.64e-164: 484: 73.84		EIF3F_HUMAN (44-328): 3.26e-64: 208: 14.48
+	Hs
		131290 K2C8_HUMAN (135-511): 1.32e-164: 478: 68.44		EIF3F_HUMAN (44-328): 3.26e-64: 208: 14.48
+	Hs
		876495 K2C6C_HUMAN (1-500): 6.92e-90: 289: 99.00		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1187826 K2C71_HUMAN (3-556): 3.72e-88: 283: 54.15		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		385310 K2C6A_HUMAN (1-500): 1.15e-85: 278: 98.60		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		566431 K2C5_HUMAN (3-479): 4.52e-85: 277: 80.75		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		1031011 K22O_HUMAN (4-488): 1.76e-69: 237: 62.60		CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00
+	Hs
		188001 K2C73_HUMAN (3-560): 3.44e-100: 315: 53.94		EIF3H_HUMAN (52-320): 2.18e-66: 214: 18.57
+	Hs
		131280 K2C6B_HUMAN (1-500): 3.19e-90: 290: 100.00		EIF3F_HUMAN (44-328): 3.26e-64: 208: 14.48
+	Hs
		131360 K2C6C_HUMAN (1-500): 6.92e-90: 289: 99.00		EIF3F_HUMAN (44-328): 3.26e-64: 208: 14.48
+	Hs
		131274 K2C6A_HUMAN (1-500): 1.15e-85: 278: 98.60		EIF3F_HUMAN (44-328): 3.26e-64: 208: 14.48