HitPredict

Interactor 1: K2C1 (P04264)
Keratin, type II cytoskeletal 1 (67 kDa cytokeratin) (Cytokeratin-1) (CK-1) (Hair alpha protein) (Keratin-1) (K1) (Type-II keratin Kb1)
Gene: KRT1

Interactor 2: SULF2 (Q8IWU5)
Extracellular sulfatase Sulf-2 (hSulf-2) (Arylsulfatase) (EC 3.1.6.1) (N-acetylglucosamine-6-sulfatase) (EC 3.1.6.14) [Cleaved into: Extracellular sulfatase Sulf-2 secreted form]
Gene: SULF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	38825040
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 644 Hs			1 870
+	Hs
		1310996 K2C78_HUMAN (119-543): 1.52e-130: 395: 55.09		SULF2_HUMAN (1-870): 0: 1352: 100.00
+	Hs
		1311038 KRT84_HUMAN (3-644): 1.04e-93: 303: 44.51		SULF2_HUMAN (1-870): 0: 1352: 100.00
+	Hs
		566420 K2C5_HUMAN (1-496): 1.95e-79: 264: 64.72		SULF2_HUMAN (1-870): 0: 1352: 100.00
+	Hs
		407316 K2C6B_HUMAN (2-512): 7e-78: 260: 62.82		SULF2_HUMAN (1-870): 0: 1352: 100.00
+	Hs
		876489 K2C6C_HUMAN (2-512): 3.57e-77: 258: 62.62		SULF2_HUMAN (1-870): 0: 1352: 100.00
+	Hs
		385301 K2C6A_HUMAN (2-512): 1.41e-74: 251: 62.43		SULF2_HUMAN (1-870): 0: 1352: 100.00
+	Hs
		1273940 K2C74_HUMAN (1-561): 2.74e-70: 239: 52.23		SULF2_HUMAN (1-870): 0: 1352: 100.00
+	Hs
		551573 K2C3_HUMAN (152-497): 3.91e-61: 216: 74.14		SULF2_HUMAN (1-870): 0: 1352: 100.00
+	Hs
		1280843 K2C1B_HUMAN (62-511): 4.3e-61: 215: 64.00		SULF2_HUMAN (1-870): 0: 1352: 100.00