Interactor 1: CD1A (P06126)
T-cell surface glycoprotein CD1a (T-cell surface antigen T6/Leu-6) (hTa1 thymocyte antigen) (CD antigen CD1a)
Gene: CD1A

Interactor 2: HLAC (P10321)
HLA class I histocompatibility antigen, C alpha chain (HLA-C) (HLA-Cw) (Human leukocyte antigen C)
Gene: HLA-C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~C1-set, C1-set~MHC_I, C1-set~MHC_I_3
Common GO terms GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0002250 - adaptive immune response
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0006955 - immune response
and 1 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 327
Hs

1 366
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024