HitPredict

Interactor 1: LCK (P06240)
Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: P85A (P26450)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: Pik3r1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 9115297
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH2, PI3K_P85_iSH2~SH2, SH2~SH3_1
Common GO terms GO:0005102 - signaling receptor binding
GO:0005829 - cytosol
GO:0005911 - cell-cell junction
GO:0010628 - positive regulation of gene expression
GO:0019903 - protein phosphatase binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 509
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1 724
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Last updated: 15 Jul 2024