HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: ECM29 (Q5VYK3)
Proteasome adapter and scaffold protein ECM29 (Ecm29 proteasome adapter and scaffold) (Proteasome-associated protein ECM29 homolog)
Gene: ECPAS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005769 - early endosome GO:0005770 - late endosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 1845
+	Hs
		650221 FGFR3_HUMAN (168-794): 3.36e-157: 479: 25.83		ECM29_HUMAN (1-1845): 0: 1288: 100.00
+	Hs
		1034165 ROR1_HUMAN (515-783): 1.17e-72: 257: 46.89		ECM29_HUMAN (1-1845): 0: 1288: 100.00
+	Hs
		285771 NTRK1_HUMAN (1-796): 0: 624: 100.00		SF3B1_HUMAN (914-1694): 4.39e-91: 327: 12.53
+	Hs
		251186 NTRK1_HUMAN (1-796): 0: 624: 100.00		RNBP6_HUMAN (692-1778): 2.48e-89: 319: 11.90
+	Hs
		411904 NTRK1_HUMAN (1-796): 0: 624: 100.00		CKAP5_HUMAN (817-1838): 5.15e-39: 162: 11.55
+	Hs
		412195 NTRK1_HUMAN (1-796): 0: 624: 100.00		CAND1_HUMAN (282-1301): 4.27e-34: 145: 12.95
+	Hs
		133919 NTRK1_HUMAN (1-796): 0: 624: 100.00		IPO5_HUMAN (260-1284): 4.41e-17: 90.2: 10.30
+	Hs
		164509 NTRK1_HUMAN (1-796): 0: 624: 100.00		TNPO2_HUMAN (1194-1843): 1.8e-15: 84.7: 13.47
+	Hs
		411430 NTRK1_HUMAN (1-796): 0: 624: 100.00		2AAA_HUMAN (1242-1703): 6.32e-14: 79.2: 13.42
+	Hs
		412386 NTRK1_HUMAN (1-796): 0: 624: 100.00		TNPO1_HUMAN (410-1097): 1.8e-12: 74.8: 12.47
+	Hs
		412360 NTRK1_HUMAN (1-796): 0: 624: 100.00		GCN1_HUMAN (642-1843): 9.24e-09: 62.9: 11.05
+	Hs
		541357 FGFR1_HUMAN (195-794): 0: 544: 26.34		2AAB_HUMAN (1115-1669): 2.23e-10: 67.7: 14.97
+	Hs
		133944 FGFR3_HUMAN (168-794): 3.36e-157: 479: 25.83		IPO5_HUMAN (260-1284): 4.41e-17: 90.2: 10.30
+	Hs
		465600 IGF1R_HUMAN (493-777): 7e-71: 255: 42.61		TNPO1_HUMAN (410-1097): 1.8e-12: 74.8: 12.47
+	Hs
		465596 IGF1R_HUMAN (493-777): 7e-71: 255: 42.61		GCN1_HUMAN (642-1843): 9.24e-09: 62.9: 11.05