HitPredict

Interactor 1: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Interactor 2: NMDZ1 (Q05586)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)
Gene: GRIN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	9670010
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0030425 - dendrite GO:0045471 - response to ethanol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 537 Hs			1 938
+	Rn
		723636 SRC_RAT (1-537): 0: 601: 67.72		NMDZ1_RAT (1-938): 0: 936: 99.25
+	Mm
		403420 SRC_MOUSE (1-537): 0: 599: 68.33		NMDZ1_MOUSE (1-938): 0: 936: 99.04
+	Hs
		412171 FYN_HUMAN (1-537): 0: 643: 100.00		NMDE2_HUMAN (4-938): 0: 661: 23.83
+	Mm
		403431 SRC_MOUSE (1-537): 0: 599: 68.33		NMDE2_MOUSE (4-938): 0: 654: 23.63
+	Hs
		412157 FYN_HUMAN (1-537): 0: 643: 100.00		NMDE1_HUMAN (2-923): 0: 602: 24.00
+	Hs
		522943 SRC_HUMAN (1-537): 0: 598: 68.21		NMDE1_HUMAN (2-923): 0: 602: 24.00