HitPredict

Interactor 1: EPHA3 (P29320)
Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)
Gene: EPHA3

Interactor 2: RUFY1 (Q96T51)
RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (La-binding protein 1) (Rab4-interacting protein) (Zinc finger FYVE domain-containing protein 12)
Gene: RUFY1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	11877430
Identification Methods	coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 983 Hs			1 708
+	Hs
		710604 EPHA3_HUMAN (1-983): 0: 1254: 100.00		MYH9_HUMAN (72-521): 1.46e-18: 93.1: 11.38
+	Hs
		336106 EPHA7_HUMAN (6-979): 0: 1200: 61.46		ZFYV9_HUMAN (639-700): 4.55e-10: 65.5: 41.27
+	Hs
		336084 EPHA4_HUMAN (8-983): 0: 1188: 62.22		ZFYV9_HUMAN (639-700): 4.55e-10: 65.5: 41.27
+	Hs
		710826 EPHB2_HUMAN (29-980): 0: 1176: 55.97		ROCK1_HUMAN (337-638): 1.87e-10: 66.4: 13.96
+	Hs
		710224 EPHA2_HUMAN (27-983): 0: 1064: 50.57		ROCK1_HUMAN (337-638): 1.87e-10: 66.4: 13.96
+	Hs
		270775 EPHA2_HUMAN (27-983): 0: 1064: 50.57		ROCK2_HUMAN (348-660): 3.22e-10: 65.7: 12.81
+	Hs
		336071 EPHA2_HUMAN (27-983): 0: 1064: 50.57		ZFYV9_HUMAN (639-700): 4.55e-10: 65.5: 41.27
+	Hs
		710278 EPHA2_HUMAN (27-983): 0: 1064: 50.57		GRDN_HUMAN (312-647): 7.59e-09: 61.4: 16.95
+	Hs
		640182 EPHA1_HUMAN (7-973): 0: 951: 42.52		GRDN_HUMAN (312-647): 7.59e-09: 61.4: 16.95
+	Hs
		720360 UFO_HUMAN (265-962): 6.36e-152: 474: 23.00		MYH2_HUMAN (65-635): 2.9e-23: 108: 12.17
+	Hs
		465525 IGF1R_HUMAN (366-890): 5.56e-139: 452: 30.63		EEA1_HUMAN (100-662): 7.07e-22: 103: 10.21
+	Hs
		587566 UFO_HUMAN (265-962): 6.36e-152: 474: 23.00		DESP_HUMAN (328-650): 9.95e-10: 64.5: 13.41
+	Hs
		720244 UFO_HUMAN (265-962): 6.36e-152: 474: 23.00		GRDN_HUMAN (312-647): 7.59e-09: 61.4: 16.95
+	Hs
		439751 INSR_HUMAN (375-880): 2.12e-136: 445: 30.32		GRDN_HUMAN (312-647): 7.59e-09: 61.4: 16.95
+	Hs
		473463 HCK_HUMAN (599-879): 3.58e-65: 230: 42.40		RUFY1_HUMAN (1-708): 5.46e-73: 252: 100.00
+	Hs
		440414 FYN_HUMAN (615-879): 1.09e-64: 229: 44.20		MYH9_HUMAN (72-521): 1.46e-18: 93.1: 11.38
+	Hs
		117127 J3QRU1_HUMAN (601-879): 1.05e-63: 227: 44.48		MYH9_HUMAN (72-521): 1.46e-18: 93.1: 11.38
+	Hs
		440337 FYN_HUMAN (615-879): 1.09e-64: 229: 44.20		DESP_HUMAN (328-650): 9.95e-10: 64.5: 13.41