HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: S100P (P25815)
Protein S100-P (Migration-inducing gene 9 protein) (MIG9) (Protein S100-E) (S100 calcium-binding protein P)
Gene: S100P

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	S_100~TAD2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 95
+	Hs
		414148 P53_HUMAN (1-393): 0: 619: 100.00		HORN_HUMAN (1-92): 2.29e-34: 125: 34.78
+	Hs
		413199 P53_HUMAN (1-393): 0: 619: 100.00		S10A1_HUMAN (2-93): 3.46e-36: 119: 53.26
+	Hs
		413280 P53_HUMAN (1-393): 0: 619: 100.00		S10AB_HUMAN (2-92): 3.01e-36: 119: 40.66
+	Hs
		413232 P53_HUMAN (1-393): 0: 619: 100.00		S10A4_HUMAN (3-95): 6.78e-34: 113: 41.94
+	Hs
		413967 P53_HUMAN (1-393): 0: 619: 100.00		FILA2_HUMAN (1-92): 1.67e-29: 111: 41.30
+	Hs
		413250 P53_HUMAN (1-393): 0: 619: 100.00		S10A2_HUMAN (2-95): 1.83e-32: 110: 40.43
+	Hs
		407558 P53_HUMAN (1-393): 0: 619: 100.00		S100B_HUMAN (1-92): 4.66e-32: 109: 50.00
+	Hs
		413509 P53_HUMAN (1-393): 0: 619: 100.00		S10AA_HUMAN (2-89): 6.19e-31: 106: 44.32
+	Hs
		413609 P53_HUMAN (1-393): 0: 619: 100.00		S10AC_HUMAN (1-92): 7.45e-31: 106: 44.57
+	Hs
		413287 P53_HUMAN (1-393): 0: 619: 100.00		S10A3_HUMAN (3-93): 1.72e-30: 105: 32.97
+	Hs
		413004 P53_HUMAN (1-393): 0: 619: 100.00		S10A8_HUMAN (1-95): 1.79e-28: 99: 34.74
+	Hs
		414397 P53_HUMAN (1-393): 0: 619: 100.00		S10AG_HUMAN (2-95): 1.06e-26: 95.7: 27.37
+	Hs
		413018 P53_HUMAN (1-393): 0: 619: 100.00		S10A6_HUMAN (3-91): 1.67e-26: 94.9: 34.83
+	Hs
		413286 P53_HUMAN (1-393): 0: 619: 100.00		S10A5_HUMAN (2-94): 6.53e-25: 91.1: 36.56
+	Hs
		414480 P53_HUMAN (1-393): 0: 619: 100.00		S10AD_HUMAN (1-83): 3.06e-24: 89.5: 28.92
+	Hs
		413694 P53_HUMAN (1-393): 0: 619: 100.00		TRHY_HUMAN (1-93): 6.37e-21: 87.2: 31.18