HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: S10AA (P60903)
Protein S100-A10 (Calpactin I light chain) (Calpactin-1 light chain) (Cellular ligand of annexin II) (S100 calcium-binding protein A10) (p10 protein) (p11)
Gene: S100A10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	S_100~TAD2
Common GO terms	GO:0005737 - cytoplasm GO:0016363 - nuclear matrix GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 97
+	Hs
		414148 P53_HUMAN (1-393): 0: 619: 100.00		HORN_HUMAN (1-97): 5.89e-32: 118: 30.69
+	Hs
		413199 P53_HUMAN (1-393): 0: 619: 100.00		S10A1_HUMAN (1-91): 3.58e-34: 114: 45.75
+	Hs
		413280 P53_HUMAN (1-393): 0: 619: 100.00		S10AB_HUMAN (2-89): 2.41e-32: 110: 38.46
+	Hs
		413967 P53_HUMAN (1-393): 0: 619: 100.00		FILA2_HUMAN (3-97): 5.27e-28: 107: 34.34
+	Hs
		413227 P53_HUMAN (1-393): 0: 619: 100.00		S100P_HUMAN (3-87): 3.87e-31: 106: 45.46
+	Hs
		413232 P53_HUMAN (1-393): 0: 619: 100.00		S10A4_HUMAN (1-87): 2.73e-29: 102: 35.56
+	Hs
		413287 P53_HUMAN (1-393): 0: 619: 100.00		S10A3_HUMAN (1-89): 4.31e-29: 101: 27.17
+	Hs
		413250 P53_HUMAN (1-393): 0: 619: 100.00		S10A2_HUMAN (1-87): 4.86e-28: 99.2: 36.67
+	Hs
		407558 P53_HUMAN (1-393): 0: 619: 100.00		S100B_HUMAN (3-87): 1.35e-26: 95.3: 37.50
+	Hs
		414397 P53_HUMAN (1-393): 0: 619: 100.00		S10AG_HUMAN (3-96): 3.45e-26: 94.6: 23.47
+	Hs
		413609 P53_HUMAN (1-393): 0: 619: 100.00		S10AC_HUMAN (3-89): 9.91e-25: 90.7: 31.11
+	Hs
		413286 P53_HUMAN (1-393): 0: 619: 100.00		S10A5_HUMAN (1-92): 6.87e-24: 88.4: 30.53
+	Hs
		413004 P53_HUMAN (1-393): 0: 619: 100.00		S10A8_HUMAN (1-93): 1.3e-23: 87.6: 25.00
+	Hs
		413018 P53_HUMAN (1-393): 0: 619: 100.00		S10A6_HUMAN (1-88): 1.8e-23: 87.2: 25.28
+	Hs
		414480 P53_HUMAN (1-393): 0: 619: 100.00		S10AD_HUMAN (3-81): 5.5e-20: 78.8: 30.49
+	Hs
		413694 P53_HUMAN (1-393): 0: 619: 100.00		TRHY_HUMAN (3-83): 7.27e-10: 55.7: 32.14