HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: S10AD (Q99584)
Protein S100-A13 (S100 calcium-binding protein A13)
Gene: S100A13

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	S_100~TAD2
Common GO terms	GO:0005507 - copper ion binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm and 2 others more... GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 98
+	Hs
		414148 P53_HUMAN (1-393): 0: 619: 100.00		HORN_HUMAN (6-89): 4.38e-30: 113: 29.89
+	Hs
		413227 P53_HUMAN (1-393): 0: 619: 100.00		S100P_HUMAN (6-91): 1.58e-30: 105: 28.09
+	Hs
		413280 P53_HUMAN (1-393): 0: 619: 100.00		S10AB_HUMAN (5-91): 2.45e-30: 105: 35.56
+	Hs
		413199 P53_HUMAN (1-393): 0: 619: 100.00		S10A1_HUMAN (7-91): 3.27e-30: 104: 37.50
+	Hs
		413509 P53_HUMAN (1-393): 0: 619: 100.00		S10AA_HUMAN (6-98): 1.63e-29: 102: 27.08
+	Hs
		413967 P53_HUMAN (1-393): 0: 619: 100.00		FILA2_HUMAN (6-89): 3.14e-25: 99.5: 33.33
+	Hs
		407558 P53_HUMAN (1-393): 0: 619: 100.00		S100B_HUMAN (6-91): 4.19e-27: 96.4: 26.97
+	Hs
		413232 P53_HUMAN (1-393): 0: 619: 100.00		S10A4_HUMAN (8-91): 1.3e-26: 95.7: 32.18
+	Hs
		413250 P53_HUMAN (1-393): 0: 619: 100.00		S10A2_HUMAN (7-91): 4.99e-26: 94.1: 32.96
+	Hs
		413287 P53_HUMAN (1-393): 0: 619: 100.00		S10A3_HUMAN (8-91): 2.53e-25: 92.2: 28.74
+	Hs
		413609 P53_HUMAN (1-393): 0: 619: 100.00		S10AC_HUMAN (6-88): 6.94e-25: 91: 33.72
+	Hs
		413004 P53_HUMAN (1-393): 0: 619: 100.00		S10A8_HUMAN (6-90): 2.08e-24: 89.9: 24.71
+	Hs
		413018 P53_HUMAN (1-393): 0: 619: 100.00		S10A6_HUMAN (8-89): 2.4e-23: 87.2: 32.53
+	Hs
		413286 P53_HUMAN (1-393): 0: 619: 100.00		S10A5_HUMAN (7-96): 6.56e-23: 86: 35.56
+	Hs
		414397 P53_HUMAN (1-393): 0: 619: 100.00		S10AG_HUMAN (3-89): 7.68e-23: 86: 31.87